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Garrison-Morton-Norman History of Medicine

LAPOINTE, Janice W.

1 entries in the GMN corpus.

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1987 CE

#13950

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones.

KORNBERG, Roger David (1947 – )
KORNBERG, Roger David (1947 – ) LORCH, Yahli Deborah LAPOINTE, Janice W.

Within the nucleosome Kornberg found that roughly 200 bp of DNA are wrapped around an octamer of histone proteins. With Yahli Lorch, Kornberg showed that a nucleosome on a promoter prevents the initiation of transcrip…