Action potentials recorded from inside a nerve fibre.

Hodgkin and Huxley were the first to succeed in inserting electrodes into a living giant nerve fiber and to measure directly the action potential within it.

In 1963 Hodgkin and Huxley shared the Nobel Prize in Physiology or Medicine with Sir John Eccles “for their discoveries concerning the ionic mechanisms involved in the excitation and inhibition in the peripheral and central portions of the nerve cell membrane.”