Identification of the cystic fibrosis gene: Cloning and characterization of complimentary DNA.

The authors first published a ‘map’ of the cystic fibrosis (CF) gene and on p. 1071, they published an illustration/schematic model of the predicted CFTR (cystic fibrosis transmembrane conductance
regulator). They first described a deletion mutation DeltaF508  (ΔF508) that was detected in both CF clones, which would result in a ‘loss’ of a phenyalanine residue at position 508 in the CF polypeptide.

Order of authorship in the original publication: Riordan, Rommens, et al, Collins, Tsui.

(Thanks to Juan Weiss for this reference and its interpretation.)