Medical flora; or, manual of the medical botany of the United States of North America. Containing a selection of above 100 figures and descriptions of medical plants, with their names, qualities, properties, history &c; and notes or remarks on nearly 500 equivalent substitutes. 2 vols.

Rafinesque was a great botanist, conchologist, archaeologist, and economist. Born in a suburb of Istanbul, he was also a world citizen and a prolific writer with 939 works to his credit. He died in extreme poverty in Philadelphia and, but for the intervention of a few friends, his body would have been sold for dissection purposes. This work describes a number of native American remedies.  Digital facsimile from the Internet Archive at this link.