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Historical Bibliography Updated: April 5, 2020

Virus interference. I. The interferon.

Publication Details

Proc. roy. Soc. B, 147, 258-67. 1957 CE.

Discovery of interferon type I, a protein that interferes with viral replication. "While working together at the NIMR, Lindenmann and Isaacs noticed that if they killed viruses using heat and applied the dead viruses to living cells, those cells became resistant to further infections from live viruses.[2] In 1957, Lindenmann and Isaacs discovered that the cells exposed to the dead viruses secreted a previously unknown substance which blocked future viral infections, which became known as interferon.[2] It was later found that interferons are too toxic for use as general antiviral drugs, but they are used to treat hepatitis C as well as some types of cancer.[2] "( Wikipedia article on Jean Lindenmann, accessed 3-2020).

Catalog MetadataReference Information
Entry Number#2578.22
Permanent Linkhttps://hom-sveltekit.fly.dev/entry/4236
Author Bio LinkWikipedia ↗
External URLvirus-interference-i-the-interferon