The maternal physician; a treatise on the nurture and management of infants, from the birth until two years old. Being the result of sixteen years' experience in the nursery. Illustrated by extracts from the most approved medical authors

The first American book on pediatrics, in the tradition of "advice books" or childcare manuals for mothers. This was the first American printed book on a medical subject written by a woman. Pages 248-75 publish a list of plants with "medicinal qualities... serviceable in the complaints of children." Tyler had the work published anonymously. See C. Gibbons, "Mary Tyler and the Maternal physician," Journal of Regional Culture, 3, 33-34.