Facets

1974 CE

#14315

"Conformational Coupling in Biological Energy Transductions." In L. Ernster et al. (eds.), Dynamics of Energy-Transducing Membranes, pp. 289-301.

In 1997 Boyer shared the Nobel Prize in Chemistry with John Walker and Jens C. Skou “for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP).” The Nobel Pr…

1974 CE

#9942

The DNA of CAENORHABDITIS ELEGANS.

Digital facsimile from PubMedCentral at this link.

1994 CE

#14261

Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization.

Order of authorship in the original publication: Baba, M., Takeshige, Baba, N., Ohsumi. In 2016 Oshuni received the Nobel Prize in Physiology or Medicine "for his discoveries of mechanisms for autophagy."

1966 CE

#14064

"Fertile" intestine nuclei.

Gurdon and Uehlinger replaced the cell nucleus of frog ova with frog intestinal nuclei to generate tadpoles, some of which became fertile adult male and female frogs. In 2012 the Nobel Prize in Physiology or Medicine …

1690 CE

#10055

A letter to a friend, upon occasion of the death of his intimate friend.

One of the most eloquent and learned discussions of death. Full annotated text from penelope.uchicago.edu at this link.

1853 CE

#7445

A narrative of travels on the Amazon and Rio Negro, with an account of the native tribes and observations on the climate, geology and natural history of the Amazon Valley.

Digital facsimile from Google Books at this link.

1977 CE

#6926

A new method for sequencing DNA.

The Gilbert-Maxam method for sequencing DNA. This paper is available from PNAS at this link. In 1980 Gilbert shared the 1980 Nobel Prize in Chemistry with Frederick Sanger and Paul Berg. Berg received half of the priz…

1999 CE

#14262

A pdf Neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila.

In 2017 Hall shared the Nobel Prize in Physiology or Medicine with Michael Rosbash and Michael W. Young “for their discoveries of molecular mechanisms controlling the circadian rhythm.” Order of authorship…

2012 CE

#11844

A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity.

Order of authorship in the original publication: Jinek, Chylinski, Fonfar, Hauer, Doudna, Charpentier. Doudna, Charpentier and colleagues showed for the first time that the CRISPR evolutionary immune tool of bacteria …

1970 CE

#6889

A restriction endonuclease from Hemophilus influenzae. II. Base sequence of the recognition site.

Discovery of the first type II restriction enzyme (HindII). Smith shared the 1978 Nobel Prize in Physiology or Medicine with Werner Arber and Daniel Nathans "for the discovery of restriction enzymes and their applicat…

1955 CE

#13685

A small particulate component of the cytoplasm.

Palade first described the association of what were subsequently determined to ribosomes with membranes. He and Keith Porter subsequently named this structure the endoplasmic reticulum. Digital facsimile from PubMedCe…

1958 CE

#6911

A three-dimensional model of the myoglobin molecule obtained by x-ray analysis.

Initial paper on the first solution of the three-dimensional molecular structure of a protein. Computing the molecular structure in 3 dimensions was possible through the use of the Cambridge EDSAC stored-program elect…

2002 CE

#8011

African American alternative medicine: Using alternative medicine to prevent and control chronic diseases.

2007 CE

#9976

African American folk healing.

1998 CE

#12553

African American midwifery in the South: Dialogues of birth, race, and memory.

1999 CE

#9224

African-American dental surgeons and the U.S. Army Dental Corps: A struggle for acceptance, 1901-1919.

Digital text from the U.S. Army Medical Department Office of Medical History at this link. (This study does not seem to have been formally published; WorldCat is uncertain of its publication date.)

1999 CE

#10315

Against the odds: Blacks in the profession of medicine in the United States.

1977 CE

#11043

An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA.

Discovery of introns. In 1993 Roberts shared the Nobel Prize in Physiology or Medicine with Phillip A. Sharp "for their discoveries of split genes." It was frequently suggested that Chow deserved a share of that prize…

1944 CE

#8385

An American dilemma: The Negro problem and modern democracy. By Gunnar Myrdal with the assistance of Richard Sterner and Arnold Rose.

Includes considerable anthropological, biological, and health data. Digital facsimile from the Internet Archive at this link.

2000 CE–2002 CE

#8081

An American health dilemma: A medical history of African Americans and the problem of race. Vol. 1: Beginnings to 1900. Vol. 2: Race, medicine and health care in the United States 1900-2000.

2006 CE

#14048

An inconvenient truth. The planetary emergency of global warming and what we can do about it.

A politician, Gore was one of the first to draw popular attention to climate change. He supplemented the best-selling book with a film and DVD with the same title. Ten years later, recognizing that in spite of its wid…

2000 CE

#13982

Architecture of RNA polymerase II and implications for the transcription mechanism.

Kornberg devoted two decades to the development of methods to visualize the atomic structure of RNA polymerase and its associated protein components. Initially, Kornberg took advantage of expertise with lipid membrane…

2001 CE

#12145

Aristotle on life and death

1927 CE

#251.1

Artificial transmutation of the gene.

Muller showed that radiation causes mutations that are passed on from one generation to the next. This was the first suggestion that inherited traits might be altered or controlled, and it created a sensation: “…

1928 CE

#194.1

Äskulap und Venus. Eine Kultur- und Sittengeschichte im Spiegel des Ärztes.

An exhaustive and well-illustrated survey of medical anthropology with emphasis on sexuality.

2005 CE

#14257

Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release.

Südhof is credited with discovering much of the machinery mediating neurotransmitter release and presynaptic plasticity, beginning with the discovery of symaptotagmins and their role in neurostrasmitter release f…

1972 CE

#257.3

Biochemical method for inserting new genetic information into DNA of simian virus 40: Circular SV40 DNA molecules containing Lambda phage genes and the galactose operon of Escherichia coli.

First recombinant DNA molecules generated. Digital facsimile from PubMedCentral at this link. In 1980 Berg was awarded half of the Nobel Prize in Chemistry "for his fundamental studies of the biochemistry of nucleic a…

1989 CE

#8087

Black women in white: Racial conflict and cooperation in the nursing profession, 1890-1950.

1971 CE

#11665

Blacks, medical schools and society.

A study of the trends in black enrollments in the nation’s medical schools, and various public and higher education factors that limited the supply of black physicians in America through the 1960s.

1933 CE

#6621

Bouquet poëtique des médecins, chirurgiens, dentistes et apothicaires.

1879 CE–1891 CE

#7591

Catalogue of the specimens illustrating the osteology and dentition of vertebrated animals, recent and extinct, contained in the Museum of the Royal College of Surgeons of England. 3 vols.: Part 1. Man: Homo sapiens.... Part II: Class Mammalia, other than man... Part III: Class Aves.

Parts 1 and 2 by Flower; part 3 by Sharpe. Digital facsimile of Part 1 from the Biodiversity Heritage Library at this link, of Part 2 at this link, and Part 3 at this link.

1983 CE

#10407

Changes in the land: Indians, colonists and the ecology of New England.

"In this work, Cronon demonstrated the impact on the land of the widely disparate conceptions of ownership held by Native Americans and English colonists. English law objectified land, making it an object of which the…

1961 CE

#256.11

Characteristics and stabilization of DNAase-sensitive protein synthesis in E. coli extracts.

With Matthaei, Nirenberg demonstrated that messenger RNA is required for protein synthesis, and that synthetic messenger RNA preparations can be used to decipher various aspects of the genetic code. Nirenberg first re…

1981 CE

#14183

Computer averaging of electron micrographs of the 405 ribosomal subunit.

Frank and colleagues developed a method that allows sorting of particle images into classes based on their orientation, as well as their structural features. Specifically Frank developed mathematical tools used for im…

1996 CE

#13565

Crystal structure of Aequorea victoria green fluorescent protein.

Tsien and colleagues published the crystal structure of the 238 A.A. long green fluorescent protein (GFP). With this data, the authors could determine what had to be modified within the protein in such a way that the …

2011 CE

#14134

Crystal structure of the β2 adrenergic receptor–Gs protein complex.

Kobilka and colleagues published the crystal structure of a beta-2 receptor forming a complex with the G protein coupled receptor. This was the first time that a complete complex of an active receptor and it's Gs prot…

1930 CE

#1038.1

Crystalline pepsin.

Crystallization of pepsin and its identity as a protein. In 1946 Northrop shared half of the Nobel Prize in Chemistry with Wendell Meredith Stanley "for their preparation of enzymes and virus proteins in a pure form."…

1983 CE

#14254

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division.

"It was at Woods Hole around July 1982, using Arbacia sea urchin eggs as his model organism, that he discovered cyclin proteins.[12] Cyclins play a key role in regulating the cell-division cycle.[16] Hunt was observin…

2002 CE

#8706

Darwin Online. The complete works of Charles Darwin, edited by John van Wyhe.

http://darwin-online.org.uk/AboutUs.html Darwin's Complete Publications Books Origin of Species, Voyage of the Beagle, Descent of Man... Articles Volcanic, Darwin-Wallace paper... Published Letters Life and letters, D…

1915 CE

#13031

Das Martyrium der heiligen Apollonia und seine Darstellung in der bildenden Kunst.

Illustrates with 100 plates various early depictions of the martyrdom of St. Apollonia, patron saint of dentistry. Saint Apollonia was one of a group of virgin martyrs who suffered in Alexandria, Egypt during a local …

1833 CE

#12866

Dentologia, a poem on the diseases of the teeth and their proper remedies. With notes, practical, historical, illustrative, and explanatory, by Eleazar Parmly.

Brown founded the first US dental school, the first US national dental society, called The American Association of Dental Surgeons, and the first US dental journal, entitled the American Journal and Library of Dental …

2003 CE

#14300

Design of a novel globular protein fold with atomic-level accuracy.

Called, "the breakthrough in computational de novo protein design." This was the proof of concept paper that computers and AI could be used to predict protein structures accurately and much faster than with convention…

1946 CE

#14138

Die Tänze der Bienen.

Von Frisch discovered the waggle dance, a particular figure-eight dance of honey bees by which successful foragers can communicate information with other members of their colony about the direction and distance to pat…

1976 CE

#2660.28

DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA.

Discovery of the first “oncogene. In 1989 Varmus and Bishop shared the Nobel Prize for in Physiology or Medicine "for their discovery of the cellular origin of retroviral oncogenes."

1977 CE

#6883

DNA sequencing with chain-terminating inhibitors.

Sanger and colleagues developed methods for rapid sequencing of long sections of DNA molecules. Sanger’s method, and that developed by Gilbert and Maxam, made it possible to read the nucleotide sequence for enti…

1976 CE

#9731

Dreams in Greek tragedy: An ethno-psycho-analytical study.

1999 CE

#13080

Early black American leaders in nursing: Architects for integration and quality. (National League for Nursing Series).

1983 CE

#8082

Educating black doctors: A history of Meharry Medical College.

1985 CE

#10785

Enzymatic amplication of B-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Polymerase chain reaction first published. With Randall K. Saiki, Stephen Scharf, Fred Faloona et al. Order of authorship in the original paper was Saiki, Scharf, Faloona, Mullis.... In 1993 the Nobel Prize in Chemist…

1956 CE

#752.4

Enzymic synthesis of deoxyribonucleic acid.

In 1959 Kornberg shared the Nobel Prize in Physiology or Medicine with Severo Ochoa "for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid." Order of authorshi…