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Garrison-Morton-Norman History of Medicine

KELLEHER, Raymond J.

1 entries in the GMN corpus.

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1990 CE

#13949

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus.

KORNBERG, Roger David (1947 – )
KORNBERG, Roger David (1947 – ) KELLEHER, Raymond J. FLANAGAN, Peter M.

Kornberg discovered that transmission of gene regulatory signals to the RNA polymerase machinery is accomplished by an additional protein complex dubbed the Mediator. As noted by the Nobel Prize committee, "the great …