Skip to main content
Garrison-Morton-Norman History of Medicine

HOWLETT, Allyn C.

1 entries in the GMN corpus.

Sort by YearSort by Title

1978 CE

#14144

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

GILMAN, Alfred Goodman (1941 – 2015)
GILMAN, Alfred Goodman (1941 – 2015)
ROSS, Elliot M.
ROSS, Elliot M. HOWLETT, Allyn C.
FERGUSON, Kenneth M.
FERGUSON, Kenneth M.

Gilman and colleagues showed that G proteins are in the cell membrane and are stimulated once a ligand (adrenaline) binds the adrenergic receptor. This system can then activate adenyl cyclase to form cyclic AMP. Digit…