ALLISON, James Patrick (1948 – )
1948 –
2 entries in the GMN corpus.
Image source Bengt Nyman from Vaxholm, Sweden · James P. Allison EM1B5525 · CC BY 2.0
1982 CE
#14266
Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.
In 1982 Allison discovered the T-cell receptor. Order of authorship in the original publication: Allison, Bloch, McIntyre.
1996 CE
#14267
Enhancement of antitumor immunity by CTLA-4 blockade.
In the early 1990s James Allison showed that CTLA-4 acts as an inhibitory molecule to restrict T-cell responses. In 1996, Allison was the first to show that antibody blockade of a T-cell inhibitory molecule (known as …