1968 –
1 entries in the GMN corpus.
Image source · Matthew Krummel · Own work · CC0
1996 CE
#14267
In the early 1990s James Allison showed that CTLA-4 acts as an inhibitory molecule to restrict T-cell responses. In 1996, Allison was the first to show that antibody blockade of a T-cell inhibitory molecule (known as …
