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CHAIN, Sir Ernst Boris (1906 – 1979)

CHAIN, Sir Ernst Boris (1906 – 1979)

1906 – 1979

6 entries in the GMN corpus.

Image source Nobel Foundation · nobelprize.org · Public domain

1940 CE

#1933.3

An enzyme from bacteria able to destroy penicillin.

Penicillinase.

1940 CE

#1934

Penicillin as a chemotherapeutic agent.

Proof of the therapeutic action in vivo of penicillin against streptococcal and other bacterial infections. Building upon Fleming’s work (No. 1933 and 10784), the consequences of which had originally been widely…

1941 CE

#1934.1

Further observations on penicillin.

First report of the chemotherapeutic action of penicillin on humans (10 cases).

1942 CE

#14282

Purification of penicillin.

Abraham and Chain first announced the purification of penicillin, a critical step before production of the drug could begin, in a two paragraph paper published on a single page of Nature on March 21, 1942. The method,…

1943 CE

#1934.2

Penicillamine, a characteristic degradation product of penicillin.

With W. Baker.

1949 CE

#12613

Antibiotics: A survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. 2 vols.

Order of authorship of the original set: H. W. Florey, Chain, Heatley, Jennings, Sanders, Abraham, M. E. Florey.