A letter … containing, a comparison between the mortality of the natural small pox, and that given by inoculation.

Jurin was an enthusiastic supporter of inoculation against smallpox, and proved statistically that the fatality of inoculated smallpox is very much less than the fatality of natural smallpox. This is one of the earliest applications of statistics to a particular socio-medical problem. Digital facsimile from Google Books at this link.