Facets

1929 CE

#12327

Glycogen formation in the liver from d- and 1-lactic acid.

The Cori cycle (also known as the lactic acid cycle), a metabolic pathway in which lactate produced by anaerobic glycolysis in muscles is transported to the liver and converted to glucose, which then returns to the mu…

1997 CE

#12326

A devotion to their science: Pioneer women of radioactivity.

1992 CE

#8773

A documentary history of biochemistry, 1770-1940. By Mikuláš Teich with Dorothy M. Needham.

2012 CE

#11844

A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity.

Order of authorship in the original publication: Jinek, Chylinski, Fonfar, Hauer, Doudna, Charpentier. Doudna, Charpentier and colleagues showed for the first time that the CRISPR evolutionary immune tool of bacteria …

1968 CE–1977 CE

#11331

Alchemy and the occult; a catalogue of books and manuscripts from the collection of Paul and Mary Mellon given to Yale University Library. Compiled by Ian MacPhail, with essays by R. P. Multhauf and Aniela Jaffé and additional notes by William McGuire. 4 vols.

1913 CE

#11438

Die Kinetik der Invertinwirkung.

The Michaelis-Menten equation, which showed that the rate of an enzyme-catalyzed reaction is proportional to the amount of the enzyme-substrate complex. This relationship between reaction rate and enzyme–substra…

1955 CE

#752.3

Enzymatic synthesis of nucleic acidlike polynucleotides.

Ochoa shared the Nobel Prize with Arthur Kornberg in 1959 for their artificial synthesis of nucleic acids by means of enzymes. Order of authorship in the original publication: Ochoa, Grunberg-Manago, Ortiz. See also O…

1934 CE

#9340

I. Un nouveau type de radioactivité. II. Séparation chimique des nouveaux radioéléments émetteur d’électrons positifs.

Discovery of artificially produced radionuclides or radioisotopes. In February 1934, the Joliot-Curies reported the first artificial production of radioactive material after discovering radioactivity in aluminum foil …

1666 CE

#6822

La chymie charitable et facile, en faveur des dames.

A book on practical chemistry, pharmacology and medicine written for the common reader by French autodidact Marie Meurdrac, La chymie charitable et facile, en faveur des dames, was the first treatise on chemistry writ…

1972 CE

#1588.11

Machina carnis: the biochemistry of muscular contraction in its historical development.

A definitive history of the development of knowledge on muscle biochemistry; valuable bibliography.

2005 CE

#11193

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: A double blind randomized placebo-controlled trial.

Order of authorship in the original paper: Taylor, Makunde, McGarry.... The authors treated infection by the parasitic worm Wuchereria bancrofti, cause of elephantiasis (lymphatic filariasis), by killing the Wolbachia…

2019 CE

#12325

Pioneering British women chemists: Their lives and contributions.

1952 CE

#3108.2

Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines.

Synthesis of 6-mercaptopurine. In 1988 Gertrude Elion shared the Nobel Prize in Physiology or Medicine with George Hitchings and Sir James Black “for their discoveries of important principles for drug treatment.…

1898 CE

#2003

Sur une substance nouvelle radio-active, contenue dans la pechblende.

The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…

1955 CE

#6928

The crystal structure of the hexacarboxylic acid derived from B12 and the molecular structure of the vitamin.

The final structure of vitamin B12. With J. Pickworth, J.H. Robertson, K.N. Trueblood, R.J. Prosen, J. G. White. In 1964 Hodgkin was awarded the Nobel Prize in Chemistry "for her determinations by X-ray techniques of …

1981 CE

#14224

The crystallization of ribsomal proteins from the 50 S subunit of the Escherichia coli and Bacillus stearothermophilus ribosome.

The authors crystallized fragments of the 50S subunit of a thermophile bacterium’s ribosome to 3 angstroms resolution. Order of authorship in the original publication: Appelt, Dyck, et al., Yonath. Digital facsi…

1906 CE

#732

The importance of individual amino-acids in metabolism.

Demonstration of the importance of tryptophan in diet. The pioneer work of Hopkins led eventually to the discovery of vitamins.

1913 CE

#1113

The origin and development of the lymphatic system.

1993 CE

#14341

Tuning the activity of an enzyme for unusual environments: Sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.

Arnold introduced a biochemical molecule manipulating technique to mimic the process of natural selection in creating new enzymes adapted to a specific catalytic reaction. She directed evolution of subtilisin E to obt…

1934 CE

#6923

X-Ray photographs of crystalline pepsin.

Bernal and Hodgkin took the first X-ray photograph of a protein structure—crystalline pepsin. They showed that crystals of pepsin give an X-ray diffaction pattern, beginning protein crystallography. This may als…