Facets

1937 CE

#11441

Toxicity of industrial organic solvents.

1785 CE

#7639

Toxicologia seu doctrina de venenis et antidotis.

Plenck provided the first classification of poisons based on origin: 1. Animal poisons. 2. Vegetable poisons. 3. Mineral poisons. 4. Poisonous vapors, gases, and dust. Plenck also issued this work in German from the s…

1579 CE

#1819.1

Tractado breve de anathomia y chirurgia.

Includes some of the first studies of the plants and botanic remedies of the New World. Second edition, Tractado breve de medicina (1592). This is an abridgement of manuscripts left in Mexico by Francisco Herná…

1578 CE

#1819

Tractado de las drogas, y medicinas de las Indias Orientales, con sus plantas debuxadas al bivo.

This is mainly a translation of Garcia d’Orta’s Coloquios (No. 1815) with the addition of some illustrations. Acosta, a Portuguese Jesuit physician and surgeon, travelled to India where he met Garcia d&rsq…

1679 CE

#10604

Tractatio med. curiosa, de ortu & occasasu transfusionis sanguins, qua haec, quae fit e bruto in brutum, a for medico penitus eliminatur; ila, quae e bruto in hominem peragitur....

The first detailed history of efforts at blood transfusion. Mercklin was one of the earliest writers to discuss the history, value, dangers, and methods of blood transfusion. He recognized and understood what we now c…

1988 CE

#7221

Traditional bush medicines: An aboriginal pharmacopoeia.

Aboriginal Communities of the Northern Territory of Australia. Collated and researched by Andy Barr, project manager; Joan Chapman, pharmacist; Nick Smith, botanist, Maree Beveridge, computer operator; Terry Knight, p…

1856 CE

#9667

Traité d'hygiène navale, ou de l'influence des conditions physiques et morales dans lesquelles l'homme de mer est appelé à vivre et des moyens de conserver sa santé.

One of the first naval manuals to include discussions of zootoxicology. Digital facsimile from BnF Gallica at this link. Much expanded second edition (1877); digital facsimile from BnF Gallica at this link.

1809 CE

#11717

Traité de la sangsue médicinale.

A 585-page treatise on this later-debunked therapy published around the time of its greatest vogue. Digital facsimile from Google Books at this link.

1836 CE–1839 CE

#1967

Traité de thérapeutique et de matière médicale. 2 vols.

“A valuable work of reference, containing a large amount of information on the various articles or the materia medica, collected from the best authorities, interspersed with much original matter” (Waring).

1839 CE

#2098

Traité des maladies de plomb ou saturnines. 2 vols.

Classical description of the diseases found among lead workers. Reporting on 1200 cases of lead poisoning, Tanquerel’s studies were so complete that later studies added little to knowledge of the symptoms and si…

1822 CE

#9326

Traité des maladies des artisans, et de celles qui résultent des diverse professions, d'après Ramazzini; Ouvrage dans lequel on indique les précautions que doivent prendre, sous le rapport de la salubrité publique et particulière, les fabricans, les manufacturiers, les chefs d'ateliers, les artistes, et toutes les personnes qui exercent des professions insalubres.

This second French edition of Ramazzini's De morbis artificum diabriba by Philibert Patissier provides so much new material on the diseases of workers in France as to virtually double the length of Ramazzini’s t…

1814 CE–1815 CE

#2072

Traité des poisons tirés des règnes minéral, végétal et animal; ou, toxicologie générale. 2 vols, each in 2 parts.

Orfila, pioneer toxicologist, was the leading medico-legal expert of his time. He was born in Minorca, studied at Valencia, Barcelona, and Paris, and was one of the founders of the Académie de Médecine. …

1877 CE–1883 CE

#8528

Traité des simples. 3 vols. Notices et extraits des manuscrits de la Bibliothèque nationale et autres bibliothèques, 1877, tome 23,1; tome 25,1; tome 26,1. Traduit par Lucien Leclerc.

Ibn al-Baytar systematically recorded the additions to pharmacy made by medieval Islamic physicians, who added between 300 and 400 types of medicines to the roughly one thousand known since antiquity. "Ibn al-Baitar&r…

1812 CE

#13631

Traité usuel du chocolat, contenant la description et la culture du cacaotier ou cacaoïer, arbre qui produit le fruit avec lequel on fabrique le chocolat, celles de la canelle, de la vanille, du salep de Perse, de l'ambre gris, du sucre, et autres substances que l'on fait entrer dans la fabrication du chocolat, les différentes façons de préparer ce commestible pour en faire un aliment recherché et propre à flatter le goût de tous les consommateurs les plus distingués, ce qui lui a fait donner, avec just tire, le sur-non de METS Des DIEUX. On y fait voir assi son utilité précieuse dans médecine.

Digital facsimile from Google Books at this link.

1906 CE

#5280

Traitement des trypanosomiases par les “couleurs de benzidine”.

Introduction of trypan-blue in the treatment of trypanosomiasis. Second paper by Mesnil and Nicolle.

1936 CE

#2025

Transfusion of cadaver blood.

Cadaver blood used in human transfusions. Prof. Shamov of Kharkov carried out the first experimental work on transfusion of cadaver blood in 1927.

1917 CE–1918 CE

#2021.1

Transfusion with preserved red blood cells.

Robertson stored blood and used it with good results to treat casualties on the battlefield.

1694 CE

#8930

Trattado unico da constituiçam pestilencial de Pernambuco, offerecido a ElRey N.S. por ser servido ordenar por seu Governador aos Medicos da America, que assistem aonde ha este contagio, que o compusessem para se conferirem pelos Coripheos da Medicina aos dictames com que he trattada esta pestilencial febre.

The first scientific description of yellow fever in Brazil by the first European physician to treat the disease in Brazil, and perhaps in all of Latin America. It includes the description of the first autopsy of a yel…

1771 CE

#12472

Travels through that part of North America formerly called Louisiana by Mr. Bossu, ... Translated from the French by John Reinhold Forster, F.A.S. Illustrated with notes relative chiefly to natural history to which is added by the translator a systematic catalogue of all the known plants of English North America, or a Flora Americae Septentrionalis together with an abstract of the most useful and necessary articles contained in Peter Loefling's travels through Spain and Cumana in South America referred to the pages of the original Swedish edition. 2 vols.

This work is a series of 21 letters that Bossu wrote to the Marquis de L’Estrade describing his life and travels in the vast Louisiana country from 1751 to 1762. His ventures ranged from Fort Chartres, in presen…

1841 CE

#1858

Treatise on the oleum jecoris aselli, or cod liver oil.

Bennett visited Paris and Germany, and learned there of the beneficial effects of cod liver oil. His book drew the attention of English medical men to the value of the oil.

1937 CE

#3661

Treatment of alcoholic cirrhosis of the liver with high vitamin therapy.

A pioneer paper on the dietary treatment of cirrhosis.

1936 CE

#6281

Treatment of human puerperal infections, and of experimental infections in mice, with prontosil.

Chemotherapeutic treatment of puerperal sepsis.

1938 CE

#1952

Treatment of pneumonia with 2-(p-aminobenzenesulphonamido) pyridine.

Clinical proof of the value of sulphapyridine. M & B 693 (sulphapyridine) treatment of pneumonia. This followed the experimental work of L. E. H. Whitby (see No. 1951).

1952 CE

#4962.3

Trente-huit cas de psychoses traitées par la cure prolongée et continue de 4560 R. P. C. R. Congr. Alien, et Neurol, de Langue Franç.

Introduction of chlorpromazine in the treatment of psychosis. Chlorpromazine was later marketed in the United States as Thorazine.

1934 CE

#8533

Tuhfat al-ahbāb: Glossaire de la matière médicale Marocaine.

1911 CE–1912 CE

#1901

Two crystalline pharmacological agents obtained from the tropical toad Bufo agua.

Isolation of bufagin. Preliminary communication in J. Amer. med. Assoc., 1911, 56, 1531-35.

1931 CE

#14209

U. S. Plant patent 1. Climbing or trailing rose. Filed Aug. 6, 1930. Issued Aug. 18, 1931.

This was the first patent granted for a life form. In response to complaints from the nursery industry that the future of the plant breeding industry was jeopardized by the “pirating” of new plant varietie…

1919 CE

#8795

Über die Anhalonium-Alkaloide I. Anhalin und Mezcalin

Synthesis of mescaline.

1887 CE

#7917

Über einige Derivate der Phenylmethacrylsäure und der Phenylisobuttersäure.

Synthesis of phenylisopropylamine, later known as amphetamine. Its stimulant effects were unknown until it was independently resynthesized by Gordon Alles.

1944 CE

#1928.3

Über Konstitution und toxische Wirkung von natürlichen und neuen synthetischen insektentötenden Stoffen.

Müller introduced Dichlordiphenyltrichlorethane (DDT) as an insecticide. With H. Martin and P. Läuger. In 1948 Müller received the Nobel Prize in Physiology or Medicine "for his discovery of the high ef…

1920 CE

#5286

Ueber chemotherapeutische Versuche mit “205 Bayer”, einen neuen trypanoziden Mittel von besonderer Wirkung.

Introduction of “Bayer 205” (germanin, suramin, naphuride).

1884 CE

#1880.1

Ueber coca.

Freud described his observations (with himself as subject) on the effects of cocaine, including its abolition of hunger and fatigue, the “exhilaration and lasting euphoria”. He also described its supposed …

1884 CE

#1878

Ueber das Antipyrin, ein neues Antipyreticum.

Introduction of antipyrine.

1855 CE

#13002

Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam.

Gaedcke, a chemist and pharmacologist, was the first to isolate the cocaine aklaloid.

1833 CE

#9668

Ueber das Gift der Fische: mit vergleichender Berücksichtigung des Giftes von Muscheln, Käse, Gehirn, Fleisch, Fett und Würsten, so wie der sogenannten mechanischen Gifte.

Discusses all then known posionsous and venomous fishes, including freshwater and marine species, and includes a "thorough review of practically all the early literature on poisonous and venomous fishes, a list of all…

1896 CE

#1889

Ueber das Pyramidon, ein Antipyrinderivat.

Filehne was responsible for the introduction of amindopyrine (pyramidon).

1841 CE–1843 CE

#1994

Ueber den Galvanismus als chemisches Heilmittel gegen örtliche Krankheiten.

Crusell began to use electrolysis as a cauterizing agent in 1839. See No. 5604.

1909 CE

#2007

Ueber Diathermie. (Transthermie, Thermopenetration.)

Nagelschmidt employed high frequency currents in treatment after the suggestions of Tesla and the work of Nernst, claiming priority over the latter in the use of this method. Nagelschmidt named this form of treatment …

1875 CE

#1869.2

Ueber die Anwendung der Salicy Isäure als Antipyreticum.

Buss introduced the clinical use of salicylic acid as an antipyretic.

1939 CE

#2010.1

Ueber die Ausbreitung und Absorption des Ultraschalls im menschlichen Gewebe und seine therapeutische Wirkung an lschias und Plexusneuralgie.

First therapeutic use of ultrasonics. With R. Richter and E. Parow.

c. 1902 CE

#12437

Ueber die Beziehungen von chemischer Constitution. Vertheilung und pharmakologischer Wirkung: Vortrag, gehalten im Verein für Innere Medicin am 12. December 1898.

In this speech Ehrlich explained how the molecular structure of a drug can define its action and function. It represents his first attempts at modifying the molecular structure of a compound in order to tailor the in …

1833 CE

#1854

Ueber die Darstellung des Atropins in weissen Krystallen.

Mein isolated atropine in pure form in 1831. Digital facsimile from Google Books at this link.

1918 CE–1919 CE

#4806

Ueber die Einwirkung der Malaria auf die progressive Paralyse.

In 1917 Wagner von Jauregg returned to the idea of the inoculation of paretics with malaria to induce pyrexia, first proposed by him in 1887 (Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen, Jb. Psychiat.…

1888 CE

#2506

Ueber die Fleischvergiftung in Frankenhausen. a.K. und den Erreger derselben.

Discovery of Salmonella enteritidis, a cause of food poisoning.

1903 CE

#2113

Ueber die Isolirung von Schlangengift-Lecithiden.

English translation in Ehrlich, Studies in immunity, 1910.

1916 CE

#2643

Ueber die künstliche Erzeugung von Karzinom.

First experimental production of tar cancer in rabbits by painting with tar products. This was the first proof of chemical carcinogenesis.

1892 CE

#2506.2

Ueber die Mosaikkrankheit der Tabakspflanze.

The Russian botanist Ivanovski demonstrated that the agent responsible for tobacco mosaic disease could pass through the finest filter then available. This was the starting point of research into the etiology of virus…

1886 CE

#2503.1

Ueber die Mosaikkrankheit des Tabaks.

Mayer was first to describe and name tobacco mosaic disease and to demonstrate its infectious nature, that it could be transferred between plants, similar to bacterial infections. Translation in Phytopathological Clas…

1900 CE

#2515

Ueber die nach Gram färbbaren Bacillen des Säuglingsstuhles.

Isolation of Lactobacillus acidophilus.

1918 CE

#9986

Ueber die Pharmaka in der Ilias und Odyssee.

Medicines and poisons in the Iliad and Odyssey.