Latest Entries
Recently added and updated annotations in the corpus.
2022 CE
#14106
Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models.
Abstract: "We evaluated the performance of a large language model called ChatGPT on the United States Medical Licensing Exam (USMLE), which consists of three exams: Step 1, Step 2CK, and Step 3. ChatGPT performed at o…
1835 CE
#14105
Nouvelles recherches sur la structure de la peau.
Beschet emphasized "the relevance of anatomic investigation to dermatologic problems" (Crissey and Parish, Dermatology and syphilology of the nineteenth century, 117). In this book the authors first described the anat…
2021 CE
#14104
Morbid undercurrents: Medical subcultures in postrevolutionary France.
"During the 1790s and beyond, medicine left the somber halls of universities, hospitals, and learned societies and became profoundly politicized, inspiring a whole panoply of different—often bizarre and shocking…
1963 CE
#14103
Recurrent Dupuytren's contracture.
Hueston described Dupuytren's diathesis, including early onset, bilateral involvement, postive family history, and presence of ectopic lesions. He noted that patents presenting Dupuytren's diathesis experience more se…
2017 CE
#14102
The role of the WI-38 cell strain in saving lives and reducing morbidity.
In 1961 "Hayflick developed the first normal human diploid cell strains for studies on human aging and for research use throughout the world. Prior to his seminal research, all cultured cell lines were immortal and an…
2013 CE
#14101
The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.
Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…
1952 CE
#14100
Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium.
A cell biologist at Johns Hopkins Hospital, Gey propagated the HeLa cell line from Henrietta Lacks' cervical tumor. This cell line, which maintained a continuous growth phase, was the first immortal human cell line to…
2018 CE
#14099
The genome of the offspring of a Neanderthal mother and a Denisovan father.
Paleogenomic study of a single bone fragment from a female hominin found in the Denisova Cave in the Altai mountains of Russia provided "direct evidence for genetic mixture between Neanderthals and Denisovans on at le…
2020 CE
#14098
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.
Expanding on previous findings by a genome wide association study of severe COVID-19, specifically with respiratory failure which had found that a gene cluster residing on chromosome 3 had a significant association wi…
1876 CE
#14097
Beobachtungen über die Befruchtung und Entwicklung des Kaninchens and Meerschweinchens.
Hensen's node. "Hensen’s research focused on the embryonic development of guinea pigs and rabbits. While studying those organisms he noticed something previously undiscovered—an enlarged area above the pri…
1929 CE
#14096
Gestaltungsanalyse am Amphibienkeim mit Örtlicher Vitalfärbung: II. Teil. Gastrulation und Mesodermbildung bei Urodelen und Anuren.
Modern fate mapping began in 1929 when Walter Vogt marked the groups of cells using a dyed agar chip and tracked them through gastrulation.
1905 CE
#14095
Grundzüge einer Biologie der menschlichen Plazenta. Mit besonderer Berücksichtig der Fragen der fötalen Ernährung.
Discovery of Hofbauer cells, oval eosinophilic histiocytes with granules and vacuoles found in the placenta, which are of mesenchymal origin, in mesoderm of the chorionic villus, particularly numerous in early pregnan…
1916 CE
#14094
The differentiation of cells as a criterion for cell identification, considered in relation to the small cortical cells of the thymus.
First use of the term "stem cells" in English. Digital facsimile from rupress.org at this link.
1868 CE
#14093
Palaeontological memoirs and notes of the late Hugh Falconer. For many years superintendent of the H.E.I. Company's botanical gardens at Suharunpoor and Calcutta. With a biographical sketch of the author. Compiled and edited by Charles Murchison. Vol. 1. Fauna Antiqua Sivalensis. Vol. II. Mastodon, elephant, rhinoceros, ossiferous caves, primeval man and his cotemporaries. 2 vols.
Falconer's writings on human antiquity appear in Vol. 2 of his Palaeontogical memoirs. Together with William Pengelly, Falconer was one of the first two scientists to visit Brixham Cave after its discovery in 1858, an…
1901 CE
#14092
Die Neven-verteilung in der Haut in ihrer Beziehung zu den Erkrankungen der Haut. Beilage zu den Verhandlungen der Deutschen Dermatologischen Gesellschaft VII Congress.
At the Seventh Congress of the German Dermatological Society held in 1901Blaschko presented observations of a rare dermatological condition involving patterned skin lesions S-shaped on the abdomen, V-shaped over the u…
1964 CE
#14091
Isolation, structure, and partial synthesis of an active constituent of hashish.
Mechoulam and Gaoni showed that the active ingredient of "one of the most widely used illicit narcotic drugs," the flowering tops of Cannabis sativa, is "pure tetrhydrocannabinol" (THC). This they called the "psychoto…
2022 CE
#14090
The contagion of liberty: The politics of smallpox in the American revolution.
"The Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to pro…
1973 CE
#14089
Rh: The intimate history of a disease and its conquest.
1938 CE
#14088
Icterus gravis (erythroblastosis) neonatorum.
Darrow was the first to identify the cause of hemolytic disease of the newborn (HDN). Three years prior to the discovery of antibodies against the Rh antigen, Darrow correctly hypothesized that the disease was caused …
1932 CE
#14087
Erythroblastosis fetalis and its association with universal edema of the fetus, icterus gravis neonatorum and anemia of the newborn.
The authors described and named this syndrome/illness of newborns for the first time, including pathological findings, clinical data, lab abnormalities, presentation and course of illness. Order of authorship in the o…
2004 CE
#14086
L’origine de la syphilis en Europe: Avant ou après 1493? / The origin of syphilis in Europe: Before or after 1493? Proceedings of an international colloquium, Toulon, France, 25–28 November 1993. Edited by Olivier Dutour, György Pálfi, Jacques Berato, and Jean-Pierre Brun.
The occasion of this meeting was the discovery in 1989 near Hyères (Var, France) of a human skeleton of the third or fourth century CE presenting lesions similar to those of syphilis. The volume contains fifty …
2006 CE
#14085
A Devonian tetrapod-like fish and the evolution of the tetrapod body plan.
The authors showed that: 1) This transitional species had a set of features representing a major departure from the pattern in more primitive sarcopterygian fishes. 2) They presented data to indicate that Tiktaalik li…
2006 CE
#14084
The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb.
In 2004 Shubin, Daeschler and Jenkins discovered the first well-preserved Tiktaalik fossils in on Ellesmere Island in Nunavut, Canada. Tiktaalik is a non-tetrapod member of Osteichthyes (bony fish) from the late Devon…
2009 CE
#14083
Ardipithecus ramidus and the paleobiology of early hominids.
The authors provide evidence that Ardipithecus may be the beginning of the evolutionary pathway that eventually led to hominids. This pathway was distinct from the evolutionary pathway that led to extant African apes.…
2009 CE
#14082
Icons of life: A cultural history of human embryos.
"Icons of Life tells the ... story of ... the Carnegie Institution of Washington's project to collect thousands of embryos for scientific study. Lynn M. Morgan blends social analysis, sleuthing, and humor to trace the…
2002 CE
#14081
A biographical dictionary of women healers. Midwives, nurses, and physicians.
2004 CE
#14080
Die Frühgeschichte der mittelalterlichen medizinischen Fachsprache im Deutschen: Bd 1: Untersuchungen. Bd 2: Wörterbuch.
2000 CE
#14079
Historiografía de la psiquiatría española.
"This work contains the bibliographic references of 1,457 published studies (from 1859 to 1997) on the history of Spanish psychiatry in all its aspects: general and local overviews, biographies and pathobiographies, e…
1984 CE
#14078
Bibliographie de l'homéopathie: Publications en langue française de 1824 à 1984.
1999 CE
#14077
The faces of homoeopathy.
"The history of homeopathic medicine as seen through the people who contributed towards its development. Focusing on homeopathy in the USA and in the UK, it traces the development of the practice through the 1800s, th…
2001 CE
#14076
The heritage of homoeopathic literature: An abbreviated bibliography and commentary.
"... an abbreviated bibliography of 915 of the best and the worst of homeopathic literature from 1810 to 2000.... the book presents the work by category (Materia Medica, Repertory, Domestic Manuals, etc.) and in chron…
1988 CE
#14075
Les livres anciens de médecine et de pharmacie. Catalogue de la Bibliothèque municipale de Toulouse.
Catalogue of books on the subjects up to 1815 held by this library.
2007 CE
#14074
Gustaf Retzius: A Biography by Thomas Lindblad. With special contributions by Gunnar Grant, Björn Afzelius, Olle Johansson & Markku Virtanen, Helge Rask-Andersen, Torstein Sjøvold. Editor: Ove Hagelin.
A finely written and superbly illustrated and produced study of Retzius's life and published works, issued in the style of Retzius's magnificent publications.
2000 CE
#14073
Three dimensional structure of the Tn5 synaptic complex transposition intermediate.
The authors provided a molecular framework for understanding transposition phenomena at the molecular level, including molecular images at 2.3Å resolution of the Tn5 transposase complexed to its respective Tn5 t…
1953 CE
#14072
Induction of instability at selected loci in maize.
McClintock (Nobel Prize 1983) discovered transposable elements or jumping genes. She found that certain parts of chromosome had switched position. This refuted the then-popular theory that genes were fixed in their po…
1902 CE
#14071
Historia de la medicina en Guatemala.
Digital facsimile from Google Books at this link. Second edition, 1958 with appendix listing physicians, surgeons and pharmacists who received degrees or taught at the University of Guatemala from1902 to 1953.
1986 CE
#14070
Bibliography of publications in legal medicine & forensic sciences relating to Sri Lanka 1811 - 1984.
1963 CE
#14069
On the aims and methods of ethology.
In this paper Tinbergen defined Tinbergen's Four Questions, or complementary categories of explanations for animal behavior. that form the basis of ethology: Causation, Ontogeny, Survival Value, and Evolution. In 1973…
2016 CE
#14068
Influenza encyclopedia: The American influenza epidemic of 1918 - 1919: A digital encyclopedia. Second edition.
ABOUT "Historians, journalists, and the public at large have long been interested in the 1918 “Spanish flu” epidemic, a dramatic chapter in American life that has spawned an impressive body of books, artic…
2015 CE
#14067
Evolution of Darwin’s finches and their beaks revealed by genome sequencing.
The authors sequenced the genome of 120 individuals representing all of Darwin’s finches. They found that a 240 kilobase haplotype encompassing the ALX1 gene, which encodes a transcription factor affecting crani…
2006 CE
#14066
Evolution of character displacement in Darwin’s finches.
Through their more than 40 year study of Darwin's finches on the Island of Daphne Major in the Galapagos, the Grants demonstrated how natural selection can drive rapid changes in body and beak size in response to chan…
1956 CE
#14065
Character displacement.
In this paper Brown and Wilson defined character displacement as follows: "Two closely related species have overlapping ranges. In the parts of the ranges where one species occurs alone, the populations of that specie…
1966 CE
#14064
"Fertile" intestine nuclei.
Gurdon and Uehlinger replaced the cell nucleus of frog ova with frog intestinal nuclei to generate tadpoles, some of which became fertile adult male and female frogs. In 2012 the Nobel Prize in Physiology or Medicine …
2007 CE
#14063
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Yamanaka (Nobel Prize 2012) and colleagues demonstrated the generation of Induced Pluripotent Stems Cells (iPS) from adult human dermal fibroblasts with the same 4 mice factors they used in GM 13287. By overexpressing…
1856 CE
#14062
Kitab-i jarrahi wa yak risalah dar kahhali [in Persian; English translation: Book on surgery with a treatise on ophthalmology]. Lithographed text.
The first Persian-language surgery and ophthalmology textbook based on Western medical science. Polak based his textbook on Joseph Maximilien Chelius’s Handbuch der Chirurgie (1830) and Handbuch der Augenheilkun…
1854 CE
#14061
Kitab fi tashrih beden al-insan [in Persian; English translation: Anatomy of the human body]. Lithographed text.
The first original Persian-language anatomy textbook based on western medical science, printed in a very small number of copies for the use of Polak’s Persian students. Polak, an Austrian physician, was responsi…
1876 CE
#14060
Explorations of the aboriginal remains of Tennessee.
The first major discussion of human skeletal pathology in American archeological samples. Jones introduced histopathological techniques in analysis of paleopathological material. Digital facsimile from Google Books at…
2022 CE
#14059
Masters of health: Racial science and slavery in U.S. medical schools.
2021 CE
#14058
Medicine and healing in the age of slavery. Edited by Sean Morey Smith & Christopher D. E. Willoughby.
1974 CE
#14057
Pop goes the café coronary.
Heimlich proposed and described the eponymous “Heimlich maneuver” for what was then called the “café coronary,” a cause of sudden death seen mostly in restaurants, or at the dinner table…