Facets

1964 CE

#1931.5

A new adrenergic beta-receptor antagonist.

Development of Propranolol, the first beta-blocker effectively used in the treatment of coronary heart disease and hypertension. R. G. Shanks, L. H. Smith and A. C. Dornhorst. In 1988 the Nobel Prize in Physiology or …

1925 CE

#3139

Blood regeneration in severe anaemia. II. Favourable influence of liver, heart and skeletal muscle in diet.

These workers showed the beneficial effect of raw beef liver upon blood regeneration in anemia. Their work paved the way for the liver diet treatment of Minot and Murphy. In 1934 Whipple shared the Nobel Prize in Phys…

2015 CE

#7855

Caring for the heart: Mayo Clinic and the rise of specialization.

The history of cardiology and cardiac surgery from the perspective of the history of the Mayo Clinic. Of special interest for details of the history of cardiac surgery in Minnesota. The book may be most remembered for…

1941 CE

#2871

Catheterization of the right auricle in man.

First investigations with the cardiac catheter as a clinical method of investigation. In 1956 Cournand in 1956 shared the Nobel Prize in Physiology or Medicine with Forssmann (No. 2858) and Richards (No. 2883.2) "for …

1707 CE

#2731

De subitaneis mortibus libri duo.

In the above work Lancisi noted cardiac hypertrophy and dilatation as causes of sudden death. He was the first to describe valvular vegetation, and his book gives a classification of the cardiac diseases then recogniz…

1929 CE

#2858

Die Sondierung des rechten Herzens.

The first cardiac catheterization on a living person. Forssmann catheterized his own heart. Historical note by N. Howard-Jones, Bull. Hist. Med.,1973, 47,524-6. English translation in Callahan, Keys & Key, Classics of…

1985 CE

#10785

Enzymatic amplication of B-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Polymerase chain reaction first published. With Randall K. Saiki, Stephen Scharf, Fred Faloona et al. Order of authorship in the original paper was Saiki, Scharf, Faloona, Mullis.... In 1993 the Nobel Prize in Chemist…

1958 CE

#1931.6

Enzymatic O-methylation of epinephrine and other catechols.

The authors discovered the enzyme "COMT" or cathecol-O-methyltransferase, and determined that it was crucial in the methylation and inactivation of adrenergic and other catecholamine type neurotransmitters. (Thanks to…

2017 CE

#12372

The coronary heart disease pandemic in the twentieth century: Emergence and decline in advanced countries.

"This book demonstrates that a pandemic of coronary heart disease occurred in North America, western and northern Europe, and Australia and New Zealand from the 1930s to about 2000. At its peak it caused more deaths t…

1947 CE

#195

The use of blood groups in anthropology.

1926 CE

#3140

Treatment of pernicious anemia by a special diet.

Introduction of raw liver diet in the treatment of pernicious anemia. This treatment ranks as one of the greatest modern advances in therapy. See also the later paper in the same journal, 1927, 89,759-66. Reprinted in…

1901 CE

#840

Un nouveau galvanomètre.

Einthoven directed much of his research to the development and perfection of recording instruments. His most famous work was in connexion with his string galvanometer, a perfection of the instrument invented by J. S. …

1900 CE

#889

Zur Kenntniss der antifermentativen, lytischen und agglutinierenden Wirkungen des Blutserums und der Lymphe.

Also: Landsteiner, "Ueber Agglutinationsercheinungen normalen menschlichen Blutes," Wiener klinische Wochenschrift, 14, 1901, 1132-1134. Landsteiner discovered that human blood contains iso-agglutinins capable of aggl…