Facets

2009 CE

#7523

History of telemedicine: Evolution, context, and transformation.

1974 CE

#8386

Hospital computer systems: How to use computers in medical centers for better patient care. Edited by Morris F. Collen.

This is the first comprehensive book on the subject. The authors describe in detail, with numerous references, the limited hospital computer systems in operation at the time both in the United States and in Europe. Th…

1964 CE

#8174

HPP-64-1 DENDRAL-64-A system for computer construction, enumeration and notation of organic molecules as three structures and cyclic graphs. Interim report to the National Aeronautics and Space Administration, December 15, (1964).

DENDRAL is considered the first expert system because it automated the decision-making process and problem-solving behavior of organic chemists. The project consisted of research on two main programs, Heuristic Dendra…

1968 CE

#11551

Hydrodynamics and hydraulics by Daniel Bernoulli and Johann Bernoulli. Translated by Thomas Carmody and Helmut Kobus.

Daniel Bernoulli’s Hydrodynamica, published in 1738, marks the first appearance of many topics central to modern science - from the kinetic theory of gases to the principles of jet propulsion. John Bernoulli&rsq…

1902 CE

#6399

Iatromathematiker vornehmlich im 15. und 16. Jahrundert.

Digital facsimile from the Internet Archive at this link.

2020 CE

#12100

IHME COVID-19 health service utilization forecasting team. Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator days and deaths by US state in the next 4 months.

This paper was published online on March 26, 2020 and updated periodically. When I added it to this database on April 2, 2020 it had been updated on March 31, 2020. At that time the paper was available from healthdata…

2020 CE

#13106

Improved protein structure prediction using potentials from deep learning.

Order of authorship in the original paper: Senior, Evans, Jumper. ABSTRACT: "Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence. This problem is…

2007 CE

#14063

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Yamanaka (Nobel Prize 2012) and colleagues demonstrated the generation of Induced Pluripotent Stems Cells (iPS) from adult human dermal fibroblasts with the same 4 mice factors they used in GM 13287. By overexpressing…

2006 CE

#13287

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Takahashi and Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become pluripotent stem cells, which have the capacity to produce many different types of cells. This they a…

1978 CE

#13969

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide (tridecamer deoxyribonucleotide/hybridization competitor/hybridon).

Zamecnick and Stephenson reported the first example of specific inhibition of gene expression by an oligonucleotide when they demonstrated that a short oligonucleotide inhibited Rous sarcoma virus replication in cell …

1883 CE

#230

Inquiries into human faculty and its development.

Galton, cousin of Charles Darwin, founded the science of Eugenics. In his important Inquiries he showed mathematically “the results of his experiments on the relations between the powers of visual imagery and of…

1981 CE

#13961

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells (embryonic stem cells/inner cell masses/differentiation in vitro/embryonal carcinoma cells/growth factors) .

Martin used a different approach that avoided in vivo alteration. She reasoned that an ES cell line might be obtained by culturing cells isolated from blastocysts in a medium that had previously been conditioned by an…

1894 CE

#643

Le mouvement.

Marey, like Muybridge (No. 650-51), was a pioneer in the use of serial pictures as a method of studying the mechanics of locomotion. English translation, 1895.

1891 CE

#638

Le travail musculaire et l’énergie qu’il représente.

Important studies on thermodynamics of muscular work.

1893 CE

#93

Leonardo da Vinci: Codice sul volo degli uccelli e varie altre materie. Pubblicato da Teodoro Sabachnikoff. Transcrizione e note di Giovanni Piumati; traduzione francese di Carlo Ravaisson-Mollien.

The scientific study of the mechanics of flight begins with Leonardo’s investigations on birds, undertaken during his attempts to build a flying machine. At the time of publication Sabachnikoff owned the manuscr…

1946 CE

#3106

Leukaemia treated with urethane compared with deep x-ray therapy.

Urethane in treatment of leukemia. With A. Haddow, I. Ap Thomas, and J. M. Watkinson.

2009 CE

#10775

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.

Gero Hütter and co-authors reported the first long-term remission or "cure" of HIV/AIDS in a human. The patient, Timothy Ray Brown also known as "The Berlin Patient" also suffered from myeloid leukemia and underw…

2019 CE

#14014

Machine learning identification of surgical and operative factors associated with surgical expertise in virtual reality simulation.

"Abstract "Importance Despite advances in the assessment of technical skills in surgery, a clear understanding of the composites of technical expertise is lacking. Surgical simulation allows for the quantitation of ps…

1996 CE

#11110

Making PCR: A story of biotechnology.

1836 CE

#604

Mechanik der menschlichen Gehwerkzeuge. 1 vol. and atlas.

A pioneering study of the physiology and biomechanics of motion and locomotion. The atlas contains four illustrations that were printed directly from actual bones embedded in plaster of Paris. This is one of the only …

1972 CE

#10505

Medical geography: Techniques and field studies. Ediited by N. D. McGlashan

Chapter 5: "Computers and mapping in medical geography" by R. W. Armstrong appears to be one of the earliest reviews of this subject.

2001 CE

#11451

Medical informatics: Computer applications in health care and biomedicine. Edited by E. H. Shortliffe, L. E. Perreault, G. Wiederhold, L. M. Fagan.

A fourth expanded edition of this textbook, edited by Shortliffe and James J. Cimino, was published as Biomedical informatics: Computer applications in health care and biomedicine (New York: Springer, 2014).

1944 CE–1960 CE

#11603

Medical physics. Edited by Otto Glasser. 3 vols.

This nearly 4000 page work in three unusually thick volumes, written by hundreds of authors, was an encyclopedia of medical physics for its time.

1948 CE

#1716

Medical statistics from Graunt to Farr.

FitzPatrick Lectures, 1941 and 1943.

1992 CE

#8382

Medicine meets virtual reality: Discovering applications for 3-D multi-media interactive technology in the health sciences. A symposium, June 4-7, 1992, San Diego, California.

The first conference on the medical applications of virtual reality.

1908 CE

#243

Mendelian proportions in a mixed population.

Hardy–Weinberg equilibrium.

1942 CE

#2700.01

Metabolic studies on neoplasm of bone with the aid of radioactive strontium.

Radioisotopic bone scanning. With B. Low-Beer, H. Friedell, and J. Lawrence.

2002 CE

#12439

Microarray-based detection and genotyping of viral pathogens.

First publication of DeRisi's microarray assay for the detection and genotyping of viral pathogens. "To address the limitations of existing viral detection methodologies, we have developed a genomic approach to virus …

1994 CE

#9718

Molecular politics: Developing American and British regulatory policy for genetic engineering, 1972-1982.

1978 CE

#9831

Multiphasic health testing services.

'In 1968 Morris F. Collen, MD and his team at KP’s Medical Methods Research (MMR) built a medical information system that peers described in the era as the most advanced of its kind. It was an aspiration of medi…

1889 CE

#233

Natural inheritance.

By the employment of statistical methods Galton propounded a “law of filial regression”. This book represents the first statistical study of biological variation and inheritance.

2000 CE

#7643

New atlas of human anatomy.

The first printed atlas of color computer images adapted from 3D images developed in the National Library of Medicine's Visible Human Project. Includes CD-ROM with 3D electronic images.

1879 CE

#9627

Notes by a naturalist on the Challenger; being an account of observations made during the Voyage of H.M.S.Challenger round the world in the years 1872-1876. Under the Command of Capt. Sir G. S.Nares and Capt. F. T. Thomson.

Includes descriptions of the natural history of Teneriffe, St. Thomas, Bermuda; Azores, Madeira, Cape Verdes; St. Paul’s Rocks and Fernando Do Norhona; Bahia; Tristan Da Cunha, Inaccessible Island; Nightingale I…

1838 CE

#145.57

Notice sur la loi que la population suit dans son accroissement.

Verhulst constructed the simplest mathematical model of a continously growing population with an upper limit to its size.

1779 CE

#9467

Observations on the management of the prevailing diseases particularly in the Army and Navy; together with a review of that in other countries, and arithmetical calculations of the comparative success of different methods of cure.

Millar promoted mathematical methods for computing the comparative success of different methods of cure. Digital facsimile from Google Books at this link.

1917 CE

#6972

On growth and form.

Thompson's description of the mathematical beauty of nature eventually inspired others, such as Alan Turing, to develop the scientific explanation of morphogenesis, the process by which patterns are formed in plants a…

1859 CE

#7388

On the construction of life-tables, illustrated by a new life-table of the healthy districts of England.

Preliminary report, describing the use of the Scheutz Engine no. 3, a Babbage-style difference engine, to prepare life tables. The report's table B1, "Life-Table of Healthy English Districts," printed from stereotype …

1914 CE

#1711

On the handicapping of the first-born.

1860 CE

#8376

On the law of mortality and the construction of annuity tables.

Gompertz-Makeham law. Makeham proposed the age-independent Makeham term that, together with the exponentially age-dependent Gompertz term, compose the Gompertz-Makeham law of mortality--one of the most effective theor…

1825 CE

#8375

On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies.

Gompertz function. "Gompertz showed that over much of the adult human lifespan, age-specific mortality rates increased in an exponential manner. Gompertz's work played an important role in shaping the emerging statist…

1945 CE

#9891

On the use of matrices in certain population mathematics.

"... the Leslie matrix is a discrete, age-structured model of population growth that is very popular in population ecology.... The Leslie matrix (also called the Leslie model) is one of the most well known ways to des…

1889 CE

#1705

On vital and medical statistics.

2017 CE

#12737

Organizing principles for the cerebral cortex network of commissural and association connections.

"Significance "The cerebral cortex supports cognition and is a structure common to all mammals. The major cortical subdivisions (its gray matter regions) are connected by a complex network of axonal connections that i…

2002 CE

#8200

Origins of cyberspace: A library on the history of computing, networking, and telecommunications.

Includes some significant early annotated references to the applictions of computing to biology and medicine.

2020 CE

#14043

Patents on life: Religious, moral, and social justice aspects of biotechnology and intellectual property. Edited by Thomas C. Berg, Roman Cholij, and Simon Ravenscroft.

2019 CE

#11398

Pathogen genomics in public health.

"An important transformation is under way in public health. Next-generation sequencing (also called “high-throughput sequencing”) is reshaping communicable disease surveillance, allowing for earlier detect…

2022 CE

#14106

Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models.

Abstract: "We evaluated the performance of a large language model called ChatGPT on the United States Medical Licensing Exam (USMLE), which consists of three exams: Step 1, Step 2CK, and Step 3. ChatGPT performed at o…

1990 CE

#14340

Phage antibodies: Filamentous phage displaying antibody variable domains.

Working in the Laboratory of Molecular Biology at Cambridge University, Winter became interested in the idea that all antibodies have the same basic structure, with only small changes making them specific for one targ…

1992 CE

#9186

Plant biomechanics: An engineering approach to plant form and function.

The first comprehensive treatment of plant biomechanics. "Niklas analyzes plant form and provides a far deeper understanding of how form is a response to basic physical laws. He examines the ways in which these laws c…

2004 CE

#8137

Primer of robotic & telerobotic surgery. Edited by Garth H. Ballantyne, Jacques Marescaux, and Pier Cristoforo Giulianotti.