Facets

1791 CE

#534.55

Abbildungen und Beschreibungen einiger Missgeburten.

Most of the plates demonstrate a progressive series of specimens with duplication anomalies of the face and head, from midfacial cleft to complete dicephalus. This arrangement of malformations into a continuous series…

1886 CE

#6084

Ablation des tumeurs flbreuses ou myomes du corps de l’utérus par la voie vaginale.

Péan’s method of morcellement of the uterus for the removal of tumors.

1828 CE

#3990

Abrégé pratique des maladies de la peau.

This book codified and published the lectures, doctrines and observations of Laurent Biett (1781-1840), the leading clinical teacher in dermatology of the early 19th century, who published very little himself. Cazenav…

1838 CE

#4028

Abrégé pratique des maladies de la peau. 3me. éd.

Laurent Théodore Biett (1781-1840), was a pupil of Alibert, Willan, and Bateman. His classic description of lupus erythematoides migrans (“Biett’s disease”) occurs on pp. 11 and 415 of the abo…

1890 CE

#4102

Acanthosis nigricans. In: Int. Atlas seltener Hautkrankheiten, Heft 4, plates x-xi

First description of acanthosis nigricans.

1940 CE

#2010.2

Acceleration of electrons by magnetic induction.

Betatron. Continued as Kerst, "The acceleration of elecrons by magnetic induction," Phys. Rev., 60 (1941) 47-52. Digital facsimile of the 1941 paper at this link.

1882 CE

#3828

Accidents consécutifs à l’ablation totale du goitre.

Reverdin produced myxedema by removal of the thyroid as a whole or in part. This confirmed the earlier work of Schiff, of which Reverdin had probably not heard. See also No. 3836.

1822 CE–1823 CE

#3912

Account of a singular variety of urine, which turned black soon after being discharged; with some particulars respecting its chemical properties.

Alkaptonuria described.

1801 CE

#3880

Accroissement singulier en grosseur des os d’un homme âgé de 39 ans. In: Mélanges de chirurgie, 407-11.

Saucerotte described before the Académie de Chirurgie in 1772 a case of what is now known to have been acromegaly. This is the first known clinical description of the disease, and is one of the five cases inclu…

1945 CE

#14284

Acetylation of sulfanilamide by liver homogenates and extracts.

Discovery of co-enzyme A and its importance for intermediary metabolism. This discovery illuminated “the process by which cells make available the energy to drive their manufacturing processes” (Judson, p.…

1912 CE

#3898

Acromegaly: a personal experience.

Mark, a medical practitioner, suffered from acromegaly from the age of 24. The condition was obvious to his friends, but Mark was 50 before he realized the cause of the symptoms of which he had kept a record for many …

1932 CE

#3903

Acromegaly.

An extensive analytical tabulation of acromegaly; 1,319 cases are reported.

1929 CE

#1138.02

Action de la préhypophyse sur le thyroïde chez le cobaye.

Simultaneously with Loeb (No. 1138.1) Aron demonstrated the thyroid-stimulating hormone (TSH) in the anterior pituitary.

1909 CE

#1204

Action de la sécrétion interne du pancréas sur différent organes et en particulier sur la sécrétion rénale.

De Meyer was apparently the first to suggest the name “insuline” for the substance then believed to be secreted by the pancreas.

1929 CE

#1168.2

Action du lobe antérieur de l’hypophyse sur la montée laiteuse.

Demonstration of the existence of a pituitary lactogenic hormone (prolactin).

1937 CE

#1925

Action protectrice des éthers phénoliques au cours de l’intoxication histaminique.

First description of structure and action of an antihistamine. In 1957 Bovet was awarded the Nobel Prize in Physiology or Medicine “for his discoveries relating to synthetic compounds that inhibit the action of …

1914 CE

#5068

Active immunization in diphtheria and treatment by toxin-antitoxin.

With A. Zingher and M. H. Serota. Park was an early advocate of diphtheria immunization with toxin-antitoxin. A second paper is in the same journal, 1915, 65, 2216-20.

1932 CE

#3203.1

Acute symptoms following work with hay.

“Farmer’s lung”.

1656 CE

#1116

Adenographia: sive, glandularum totius corporis descriptio.

Wharton described the duct of the submaxillary salivary gland (“Wharton’s duct”). He described the thyroid more accurately than his predecessors, naming it. He also described “Wharton’s j…

2013 CE

#14353

Adrenaline.

A history and survey.

1943 CE

#1174

Adrenocorticotropic hormone.

Choh Hao Li and colleagues Isolated pure adrenocorticotropic hormone (ACTH) from sheep pituitary glands.

1786 CE

#4016

Aetiologie der Krätze.

Wichmann definitely established the parasitic aetiology of scabies.

1952 CE

#2578.9

Agammaglobulinemia.

First report.

1925 CE

#2603

Allergic diseases; diagnosis and treatment of bronchial asthma, hay fever, and other allergic diseases.

In his important studies of asthma, Storm van Leeuwen demonstrated that in the great majority of patients allergens are the cause of the condition and also that patients are sensitive to mold spores. He experimented w…

1930 CE

#2653

Allergie des Lebensalters, die bösartigen Geschwülste.

Important study of the age and sex incidence of cancer.

1957 CE

#4154.5

Alopecia mucinosa. Inflammatory plaques with alopecia characterized by root-sheath mucinosis.

Follicular mucinosis.

1769 CE

#3807

An account and method of cure of the bronchocele or Derby neck.

Prosser gave the prescription of a powder containing calcined sponge, to be taken for the cure of goitre. This is probably the first recorded use of an iodine preparation in England.

1828 CE

#4452

An account of a case of osteo-sarcoma of the left clavicle, in which exsection of that bone was successfully performed.

Valentine Mott was an outstanding figure in American surgery during the first half of the 19th century. A pupil of Astley Cooper, he particularly distinguished himself in vascular surgery and in operations involving t…

1754 CE

#4014

An account of an extraordinary disease of the skin and its cure. Extracted from the Italian of Carlo Crusio, with a letter of the Abbé Nollet to Mr. William Watson by Robert Watson.

The early history of scleroderma is confused with that of leprosy, ichthyosis, and keloid. Crusio appears to be the first to differentiate it. Gintrac in 1847 coined the term “scleroderma”. It is now inclu…

1797 CE

#3930

An account of two cases of the diabetes mellitus: With remarks, as they arose during the progress of the cure. To which are added, a general view of the nature of the disease and its appropriate treatment, including observations on some diseases depending on stomach affection; and a detail of the communications received on the subject since the dispersion of the notes on the first case....And some observations on the nature of sugar by William Cruickshank. 2 vols.

Rollo reported the success of a meat diet in the treatment of diabetes. He was the first to take Matthew Dobson's discovery of glycosuria in diabetes mellitus and apply it to managing metabolism.[He was a pioneer in t…

1746 CE

#3166.1

An account of what appeared on opening the body of an asthmatic person.

Probably the earliest comprehensive clinical and pathological account of emphysema.

1890 CE

#2622

An address on a characteristic organism of cancer.

“Russell’s bodies.”

1970 CE

#2578.40

An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity.

Hypervariable regions of “Ig.”

2003 CE

#7323

An atlas of hair pathology—with clinical correlations.

1939 CE

#2576.8

An electrophoretic study of immune sera and purified antibody preparations.

Antibodies shown to be gamma globulins.

1923 CE

#1135

An elementary chemical study of the parathyroid glands of cattle.

Hanson isolated the first really potent parathyroid extract.

1814 CE

#12762

An essay on the venereal diseases which have been confounded with syphilis, and the symptoms which exclusively arise from that poison. Illustrated by drawings of the cutaneous eruptions of true syphilis, and the resembling diseases.

Carmichael "subdivided venereal infections into four major classes, each of which he maintained had a distinct exciting poison, a peculiar primary manifestation and a separate series of constitutional affections. From…

1933 CE

#2662

An exhibit of important books, papers, and memorabilia illustrating the evolution of the knowledge of cancer.

1905 CE–1906 CE

#1180

An experimental enquiry into the factors which determine the growth and activity of the mammary glands.

In their classic paper on the mammary gland, these workers attributed its changes during pregnancy to the fetus.

1903 CE–1904 CE

#2558

An experimental investigation of the rôle of the blood fluids in connection with phagocytosis.

Wright and Douglas showed the existence of thermolabile substances (opsonins) in normal and immune serum.

1731 CE

#4013

An extract from the minutes of the Royal Society, March 16, 1731, containing an uncommon case of a distempered skin.

First known description of Ichthyosis hystrix, a group of rare skin disorders in the ichthyosis family of skin disorders characterized by massive hyperkeratosis with an appearance like spiny scales. Digital facsimile …

1998 CE

#7322

An illustrated guide to skin lymphoma.

1798 CE

#2529.3

An inquiry into the causes and effects of the variolae vaccinae.

Jenner established the fact that a “vaccination” or inoculation with vaccinia (cowpox) lymph matter protects against smallpox. He performed his first vaccination on May 14, 1796. The above work, describing…

1915 CE

#2571

An investigation on the nature of ultra-microscopic viruses.

Twort discovered discovered bacteriophages, a type of virus that attacks bacteria (the term bacteriophage was coined by Félix d’Herelle, who in 1917 independently confirmed Twort’s discovery). The d…

1923 CE

#1183

An ovarian hormone.

Isolation of the active principle of the ovarian hormone (oestrin). More detailed account in J. biol. Chem., 1924, 61, 711-23.

1892 CE

#4109

An undescribed variety of hereditary oedema.

Independently of Nonne (No. 4106) Milroy described congenital edema of the legs; it has been given the eponym “Milroy’s disease”.

1926 CE

#4151.2

An unusual type of pemphigus, combining features of lupus erythematosus.

Pemphigus erythematodes. “Senear–Usher syndrome”.

1944 CE

#3976.1

Analyse du mécanisme de l’action hypoglycémiante de p-aminobenzène-sulfamido-isopropylthiodiazol (2254 RP).

Loubatières initiated work on the hypoglycaemic sulphonamides. See his historical account in Ann. N.Y. Acad. Sci., 1957, 71, 4-11.

1806 CE

#1695

Analyse et tableaux de l’influence de la petite vérole sur la mortalité à chaque âge, et de celle qu’un préservatif tel que la vaccine peut avoir sur la population et la longevité.

Duvillard showed statistically the effect of smallpox vaccination on the mortality rate. Digital facsimile from Google Books at this link.

1917 CE

#2601

Anaphylaxie et antianaphylaxie.

English translation, 1919.