Facets

1925 CE–1926 CE

#2918

Concerning the pathology of some arterial diseases.

Klotz, eminent Canadian pathologist, is particularly remembered for his contributions to the subject of arteriosclerosis.

1908 CE

#9645

Concerning the relationship between the strength of acids and their capacity to preserve neutrality.

Henderson-Hasselbalch equation for the determination of pH concentration in the blood. See Hasselbalch's paper. Digital facsimile of Henderson's paper from the American Journal of Physiology at this link. Henderson's …

1948 CE

#11766

Congenital anaomies of the heart and great vessels. Clinicopathologic study of 132 ases.

An extensively illustrated pathological-anatomical and physiological presentation with an historical approach.

1927 CE

#2856

Congenital cardiac disease by Maude Abbott. IN: Modern medicine: Its theory and practice, edited by Sir William Osler, assisted by Thomas McCrae. 3rd ed., 4, 612-812.

1945 CE

#3044

Congenital coarctation of the aorta and its surgical treatment.

Crafoord and Gross (No. 3044.1) pioneered this basic operation in cardiac and pediatric surgery.

1982 CE

#12368

Congenital heart disease: Benchmark papers in human physiology.

1965 CE

#11587

Congenital heart disease: Correlation of pathologic anatomy and angiography. 2 vols.

With Lewis Carey and Richard Lester.

1950 CE

#2882

Congenital heart disease.

A new classification proposed.

1947 CE

#2878

Congenital malformations of the heart.

This 618-page work, which required ten years to write, was the first "definitive textbook" of congenital heart defects, a subspecialty of pediatrics that Taussig created. The second edition, published in 1960, was ess…

1933 CE

#2899

Congestive heart failure and angina pectoris: The therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of thyroid toxicity.

Thyroidectomy for congestive heart failure and angina pectoris. With D. D. Berlin.

1945 CE

#3105

Conglutination test for Rh sensitization.

Conglutination test.

1925 CE

#2917

Consideraciones sobre la denominación de “Enfermedad de Ayerza”.

In 1901 Argentinian physician Abel Ayerza (1861-1918) lectured on the syndrome of chronic cyanosis, dyspnoea, erythremia, and sclerosis of the pulmonary artery, “Ayerza’s disease” (cor pulmonale). He…

1935 CE

#2023

Continuous drip blood transfusion.

Introduction of the slow-drip method of blood transfusion.

1888 CE

#2792

Contribution à l’anatomie pathologique de la maladie bleu (cyanose cardiaque).

The “tetralogy of Fallot.” He gave an important, but not the first, account of this condition (see Nos. 2726.1 & 2761). Abstract translation in Willius & Keys, Cardiac classics, 1941, pp. 689-90.

1955 CE

#3047.7

Controlled cross circulation for direct-vision intracardiac surgery; correction of ventricular septal defects, atrioventricularis communis, and tetralogy of Fallot.

Controlled cross circulation (human heart–lung “machine”) for intracardiac surgery.

1954 CE

#3047.6

Controlled cross circulation for open intracardiac surgery; physiologic studies and results of creation and closure of ventricular septal defects.

Warden and colleagues undertook the first repair of various cardiac anomalies. With M. Cohen, and R.C. Read.

1974 CE

#11553

Corpuscles: Atlas of red blood cell shapes.

A spectacular oversize atlas reproducing 121 photographs of erythrocytes as visualized with a scanning electron microscope. The first edition was published in English, followed by an edition in French in 1976.

1844 CE–1845 CE

#267.1

Cours de microscopie. 1 vol. and atlas.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotog…

1966 CE

#12369

Creation of an atrial septal defect without thoracotomy. A palliative approach to complete transposition of the great arteries.

Rashkind balloon atrial septostomy to treat transposition of the great vessels.

2021 CE

#13478

CRISPR-Cas9 gene editing for sickle cell disease and ß-thalassemia.

First application of CRISPR gene editing in the successful cure of diseases. Order of authorship in the original publication: Frangoul, Altshuler, Cappellini. (Thanks to Juan Weiss for this reference and its interpret…

1948 CE

#1929.3

Curare-like action of polymethylene bis-quaternary ammonium salts.

Methonium compounds. See also the same journal, 1948, 162, 810.

1556 CE

#3049

Curationum medicinalium centuriae quatuor.

Contains (Cent. iii, curat. 70, p. 286) first recorded case of purpura as a separate entity, not associated with fever. English translation of this section in Major, Classic descriptions of disease, 3rd. ed., 1945, p.…

1945 CE

#3103

Cyanosis in infants caused by nitrates in well water.

Methemoglobinemia. Comly first suggested the above hypothesis, since proved valid.

1923 CE

#11685

Cyanosis.

"In their monumental 1945 paper on the surgical treatment of malformations of the heart, Alfred Blalock and Helen Taussig refer to this monograph: 'Lundsgaard and Van Slyke in their classic studies on the causes of cy…

1934 CE

#3747

Das Beriberi-Herz.

Wenckebach wrote a classic account of the heart in beriberi.

1836 CE

#3115

Das Blut in mehrfacher Beziehung physiologisch und pathologisch untersucht.

Nasse gave the first clear description of anemia in pregnancy; he also noticed erythrocyte sedimentation in certain pathological conditions.

1910 CE

#11674

Das Elektrokardiogramm des gesunden and kranken Menschen.

The first comprehensive monograph on electrocardiography in any language.

1938 CE

#6915

Das Gleichgewicht zwischen Hämoglobin and Sauerstoff.

Haurowitz discovered that crystalline deoxyhemoglobin changes in shape and color on reaction with oxygen, suggesting that it is a molecular lung.

1918 CE

#3849

Das Myxödemherz

First systematic study of the characteristic changes of the heart in myxedema.

1919 CE

#2849

Das Myxödemherz.

First attempt to restore the heart’s action by intracardiac injection.

1618 CE

#10502

De affectionibus cordis. Libri tres. Qvorum primus agit de naturalibus. Secundus & tertius De preternaturalibus, de paliptatione nempe, & syncope, atque earum curatione.

The first book on heart disease. "The recognition of heart disease as of clinical interest and importance was exceedingly slow. In 1618, one hundred and eleven years after the pioneer publication of Benivieni of the p…

1749 CE

#2732

De aortae venaeque cavae gravioribus quibusdam morbis.

1746 CE

#862

De ferrearum particularum sede in sanguine.

Discovery of iron in the blood.

1862 CE

#2704

De l’asphyxie locale et de la gangrène symétrique des extrémités.

First description of “Raynaud’s disease.” Raynaud was the first to describe this disorder, which causes extreme constriction of the peripheral blood vessels resulting in discoloration of the fingers,…

1842 CE

#864

De l’origine des globules du sang, de leur mode de formation et de leur fin.

Announces the discovery of the blood platelets.

1871 CE

#3766.1

De la microcythémie

Vanlair and Masius were the first to suggest the concept of hereditary hemolytic anemia. Their paper was republished in book form, Brussels, 1871.

1873 CE

#876

De la numération des globules rouges du sang I. Des méthodes de numération. II. De la richesse du sang en globules rouges dans les différentes parties de l'arbre circulatoire.

The beginning of blood-counting techniques. In his thesis Malassez provided the initial description of the hemocytometer, which he invented, but which was named by Gowers, who modified it in 1877. The trade issue of t…

1940 CE

#3040

De la résection du carrefour aortico-iliaque avec double sympathectomie lombaire pour thrombose artéritique de l’aorte; le syndrome de l’oblitération termino-aortique par artérite.

Obliteration of the abdominal aorta.

1916 CE

#2846

De la sténose mitrale avec communication interauriculaire.

“Lutembacher syndrome”.

1889 CE

#2795

De la tachycardie essentielle paroxystique.

Bouveret introduced the term “Paroxysmal tachycardia”. Partial English translation in No. 2241.

1698 CE

#10657

De motu cordis adversaria analytica.

In this pioneering experimental study of coronary function, describing the first experimental tying of a coronary vessel, Chirac demonstrated that cardiac arrest occurs in response to coronary ligation. “A speci…

1728 CE

#2973

De motu cordis et aneurysmatibus.

Lancisi noted the frequency of cardiac aneurysm and showed the importance of syphilis, asthma, palpitation, violent emotions, and excess as causes of aneurysms. He was the first to describe cardiovascular syphilis. La…

1817 CE

#9871

De nova infusionis methodo. Dissertatio inauguralis medico-chirurgica....

Eduard von Graefe’s medical thesis described the method devised by his brother, Carl Ferdinand von Graefe (1787-1840), for transfusing blood or other liquids into the blood vessels. The work includes an illustra…

1603 CE

#2726

De pulsibus libri tres nunc primum in lucem editi.

Sassonia emphasized the importance of the pulse in diagnosis, and provided the first recorded description of heart block. Pages 57-61 contain graphic representations of the pulse using dashes of unequal length. Digita…

1858 CE

#935

De sanguine oxydo carbonico infesto.

Investigation of the blood gases.

1761 CE

#2276

De sedibus, et causis morborum per anatomen indagatis libri quinque. 2 vols.

Morgagni was the founder of modern pathological anatomy. The work was completed in Morgagni’s 79th year and consists of a series of 70 letters reporting about 700 cases and necropsies. As best he could, he corre…

1707 CE

#2731

De subitaneis mortibus libri duo.

In the above work Lancisi noted cardiac hypertrophy and dilatation as causes of sudden death. He was the first to describe valvular vegetation, and his book gives a classification of the cardiac diseases then recogniz…

1624 CE

#2971

De tumoribus praeter naturam libri quinque. Ex instructissima Bibliotheca Ranchiniana eruti, & publici iuris facti, cura & studio Henric Gras...Accessit Ioannis Saportae Tractatus de lue venerea.

IN 1554 Saporta gave the earliest description of an aortic aneurysm. Many years after Saporta's death Henri Gras of Lyon discovered the manuscript of Saporta's book, and edited it for publication. Digital facsimile fr…

1554 CE

#23

De vesicae renumque morbis. De purgantibus medicamentis. De partibus corporis humani...

First printed edition in Greek, edited by Jacques Goupyl. Rufus was a Greek physician who lived during the rule of Trajan. He wrote wrote treatises on dietetics, pathology, anatomy, and patient care. His De partibus c…

1587 CE

#10660

De virtutibus et viciis cordis libri tres. Primus agit de virtutibus & functionibus cordis. Secundus de palpitatione cordis. Tertius de syncope.

The earliest separate treatise on cardiac physiology and pathology. Digital facsimile from Google Books at this link.