Skip to main content

Latest Entries

Recently added and updated annotations in the corpus.

1979 CE

#14206

Experimental evidence in support of an extra-terrestrial trigger for the Cretaceous-Tertiary extinctions. (Abstract).

Iridium is a very rare element in the Earth's crust, but is found in anomalously high concentrations (around 1000 times greater than normal) in a thin worldwide layer of clay marking the boundary between the Cretaceou…

2004 CE

#14205

Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst.

The authors in Korea, led by Woo-suk Hwang, reported the cloning of a human blastocyst using somatic cell nuclear transfer, and deriving pluripotent embryonic stem cells from that cloned blastocyst. In doing so they c…

1860 CE

#14204

A medico-legal treatise on malpractice and medical evidence, comprising the elements of medical jurisprudence.

The first treatise on malpractice published in the United States and the first book to provide observations on the physician as an expert witness in malpractice cases. Digital facsimile from wellcomecollection.org at …

1934 CE

#14203

The anemias.

1966 CE

#14202

Mendelian inheritance in man; catalogs of autosomal dominant, autosomal recessive, and X-linked phenotypes.

Last expanded printed edition: 12th edition, 3 vols., 1998. "Dr Victor A. McKusick wrote an article in 1962 for the Quarterly Review of Biology titled ‘On the X Chromosome of Man’ (1). At that time, X-link…

2017 CE

#14201

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.

Prior to their development of the mRNA vaccine for Covid-19, Karikó and Weissman (Nobel Prize 2023) and colleagues used a novel mRNA vaccine, with base modifications created in their laboratory, to generate a p…

2023 CE

#14200

Ultra-fast deep-learned CNS tumour classification during surgery.

Published "open access" 11 October 2023. https://www.nature.com/articles/s41586-023-06615-2 "Abstract: "Central nervous system tumours represent one of the most lethal cancer types, particularly among children1. Prima…

1827 CE

#14199

Méthode nouvelle pour le traitement des déviations de la colonne vertébrale; précédée d'un examen critique des divers moyens employés par les orthopédistes modernes.

Digital facsimile from Google Books at this link.

1967 CE

#14198

Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.

Jay Seegmiller and his colleagues at NIH discovered that the rare genetic disease, Lesch–Nyhan syndrome, was due to a profound deficiency of an enzyme known as hypoxanthine guanine phosphoribosyltransferase, or …

1964 CE

#14197

A familial disorder of uric acid metabolism and central nervous system dysfunction.

Lesch-Nyhan syndrome, a rare inherited disorder that affects about 1 in 380,000 live births. In their summary the authors described this as a new "syndrome consisting of hyperuricemia, mental retardation, choreoatheto…

1854 CE–1856 CE

#14196

Oeuvres anatomiques, physiologiques et médicales de Galien. Traduites sur les textes imprimés et manuscrits accompagnées de sommaires, de notes, de planches et d'une table des matières. Précédées d'une introduction ou étude biographique, littéraire et scientifique sur Galien par Charles Daremberg. 2 Volumes.

Digital facsimile from the Hathi Trust at this link.

1924 CE

#14195

The scrotum as a temperature regulator for the testes.

Moore and Quick established that the scrotal sac, and its ability to expand or contract, helps to regulate the temperature of the testes. Through this mechanism it enables sperm production and supports the viability o…

1878 CE

#14194

La théorie des germes et ses applications à la médecine et à la chirurgie. Lecture faite à l'Académie de médecine par M. Pasteur en son nom et au nom de MM. Joubert et Chamberland ....

In this speech Pasteur first introduced the term "germ theory" and defined its applications in medicine, surgery, and infectious disease. The speech was first published in condensed form in Comptes rendus...de l'Acad&…

1971 CE

#14193

The American Association of Orthodontists: The biography of a specialty organization.

1929 CE

#14192

The action of ephedrine, pseudoephedrine and epinephrine on the bronchioles.

Swanson showed that just 0.01 mg. of epinephrine was as vasconstrictive as 2 mg. of ephedrine and 4 mg. of pseudoephedrine. He also showed that all three of these drugs have bronchodilator properties, but epinephrine …

1959 CE

#14191

A history of the American Dental Association 1859-1959.

1958 CE

#14190

History of dental laboratories and their contributions to dentistry.

1982 CE

#14189

Corps infirmes et sociétés : Essais d'anthropologie historique.

Translated into English by William Sayers as A history of disability. New foreward by David T. Mitchel and Sharon L. Snyder. Ann Arbor: The University of Michigan Press, 2019. "The first book to attempt to provide a f…

1861 CE

#14188

Stammering and stuttering, their nature and treatment.

1857 CE

#14187

A treatise on the cure of stammering, with a general account of the various systems for the cure of impediments in speech and a notice of the life of the late Thomas Hunt.

1980 CE

#14186

Speech disorder in nineteenth century Britain. The history of stuttering.

2020 CE

#14185

Single particle cryo-EM at atomic resolution.

The authors located individual atoms with a protein molecule for the first time using cryo-EM. This was the highest resolution imaging of a single protein molecule achieved to date using cryo-EM. Order of authorship o…

1984 CE

#14184

Cryo-electron microscopy of viruses.

Dubochet and colleagues introduced "Dubochet's vitrification method" to vitrify water by cooling it so rapidly that it solidified to form a glass instead of crystals. Using this method, the authors published the first…

1981 CE

#14183

Computer averaging of electron micrographs of the 405 ribosomal subunit.

Frank and colleagues developed a method that allows sorting of particle images into classes based on their orientation, as well as their structural features. Specifically Frank developed mathematical tools used for im…

1975 CE

#14182

Three-dimensional model of purple membrane obtained by electron microscopy.

The invention of Cryogenic electron microscopy (cryo-EM). The novel technique was achieved by "by applying the method to tilted specimens, and using the principles put forward by De Rosier and Klug (GM - 13935), for t…

1858 CE

#14181

Compendium der Biochemie. 2 vols.

Kletzinsky coined the term "Biochemie" (biochemistry). Digital facsimile from the Hathi Trust at this link.

1832 CE

#14180

Traité theorique et pratique de la ligature des artères.

Manec was head of anatomy at the Facultè de Médecine de Paris and a surgeon at the Salpetrière. He wrote text of his atlas on ligations of arteries in the first person based upon his experience pe…

1812 CE

#14179

Anatomie du gladiateur combattant, applicable aux beaux arts . . . .

Salvage's 21 plates after his own drawings "are based on three casts of bodies dissected to different anatomical layers and set in the pose of the Borghese Gladiator. For these casts he preferred to use the bodies of …

1813 CE

#14178

Recherches historiques sur la médecine des chinois.

The first Western history of Chinese medicine. Lepage, a pupil of Pierre Sue, was a friend and colleague of pioneer sinologist Jean-Pierre Abel-Rémusat. In his medical thesis Lepage presented an overview of wha…

1825 CE

#14177

Commentatio de vera materiae sanguini purpureum colorem impertientis natura.

Engelhart’s dissertation, presented before the medical faculty at the University of Göttingen, contains the first determination of the molecular mass of a protein (hemoglobin). Engelhart proved that the rat…

1815 CE

#14176

Sketches of the medical schools of Paris.

Crosse, a British surgeon whose name appears without the final "ed" on the title page, was a British surgeon who spent the winter of 1814-15 in Paris, where he wrote numerous letters to friends in london and Dublin de…

1985 CE

#14175

Identification of a novel force-generating protein, kinesin involved in microtubule based motility.

The authors discovered and named a second motor protein, and named it kinesin. Digital text from PubMedCentral at this link. Order of authorship in the original publication: Vale, Reese, Sheetz. (Thanks to Juan Weiss …

1965 CE

#14174

Dynein: A protein with adenosine triphosphate activity from cilia.

IN 1963 Gibbons discovered a novel protein on microtubules. In 1965 he purified two regions of the protein, known as its two "arms" and named the protein dynein. This protein converts the chemical energy stored in ATP…

1936 CE

#14173

Dermographisme et mastocytose.

Sézary and colleagues first reported systemic mastocytosis.

1887 CE

#14172

Beiträge zur Anatomie und Pathogenese der Urticaria simplex und Pigmentosa.

Unna reported that skin lesions of urticaria pigmentosa contained numerous mast cells. This was the first report of a primary mast cell disorder. Digital facsimile from deutsche-digitale-bibliothek.de at this link.

1992 CE

#14171

Sex reassignment. Thirty years of international follow-up studies after sex reassignment surgery: A comprehensive review, 1961-1991. Translated from German into American English by Roberta B. Jacobson and Alf B. Meier.)

Includes an extensive bibliography of printed and online sources. https://web.archive.org/web/20070520063824/http://www.symposion.com/ijt/pfaefflin/1000.htm

1958 CE

#14170

Homosexuality, transvestism and change of sex.

Probably the first publication to illustrate the stages of surgical transition from male to female, and to discuss the risks then involved in the operations. Digital facsimile from the Hathi Trust at this link.

2022 CE

#14169

The molecular epidemiology of multiple zoonotic origins of SARS-Co-V-2.

Abstract: "We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early in the coronavirus disease 2019 (COVID-19) pandemic. We show that SARS-CoV-2 genomic diversity before …

2022 CE

#14168

The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic.

Worobey and colleagues showed: 1) The earliest case of an abnormal pneumonia was first reported to the World Health Organization on Dec. 31, 2019. 2) Using basic epidemiology going back to the now iconic plot maps dra…

1900 CE

#14167

The Croonian lecture. -- On immunity with special reference to cell life.

Ehrlich's "lock and key" theory of antibody antigen relationship, or interaction, in which the toxin molecule (i.e the antigen) binds to the cell receptor, and then the antibody binds in a lock and key manner to the t…

1967 CE

#14166

Christine Jorgensen: A personal autobiography.

1863 CE

#14165

Der Gebrauch des Spektroskopes zu physiologischen und ärztlichen Zwecken.

The first monograph on medical spectroscopy. After Hoppe-Seyler published the first paper on the application of spectroscopy to blood chemistry in 1862 (No. 870), Valentin decided to publish his own contributions to t…

1923 CE

#14164

Vocabularium anatomiae latine-arabice.[Qāmūs al-tašrīḥ Lātīnī-‘Arabī].

1825 CE

#14163

Mémoire sur l'acupuncture, suivi d'une série d'observations recueillies sous les yeux de M. Jules Cloquet by M. Morand.

Little is known about Morand. He refers to his teacher, Jules Cloquet throughout. Cloquet's book on acupuncture was published the following year in 1826. (No. 6829). Digital facsimile of Morand's book from BnF Gallica…

1907 CE

#14162

The journal of Dr. John Morgan of Philadelphia from the city of Rome to the city of London 1764. Together with a fragment of a journal written at Rome, 1764, and a biographical sketch.

Digital facsimile from the Internet Archive at this link.

1973 CE

#14161

Transplantation of isolated pancreatic islets into the portal vein of diabetic rats.

Lacy and colleagues showed that transplanation of murine pancreatic islet tissue into the portal vein of diabetic rats of the same inbred strain normalized the sugar levels and urine output of the rats that received t…

1900 CE

#14160

Histologie du pancreas. In Traité d'anatomie humaine, edited by Paul Julien Poirier & Adrien Charpy, vol. 4, pp. 821-831.

Laguesse, who in 1893 named the islets of Langerhans, established in this work that the islets of Langerhans were the seat of internal secretion of the pancreas. On figures 425 and 427 he drew that are now called "the…

1861 CE–1867 CE

#14159

Atlas des peripherischen Nervensystems des menschlichen Körpers / Atlas du système nerveux périphérique du corps humain. Mit einem Vorwort von Prof. Dr. Th. W. L. Bischoff, nach der Natur photographirt von Joseph Alb. 10 parts.

Issued in 10 parts in folio (510 x 360 mm). Includes 46 large-format original photographs mounted on sheets of cardboard.

2023 CE

#14158

Freud's antiquity: Object / Idea / Desire. Exhibition catalogue 25/02/2023 -16/07/2023. Edited by Richard Armstrong, Miriam Leonard, Daniel Orrells, Tom DeRose & Karolina Heller.

An interpretive exhibition catalogue explaining the relationship of Freud's large collection of antiquities preserved in the Freud Museum to ideas that Freud developed in psychoanalysis.

1969 CE

#14157

Oeuvres d'Ambroise Paré conçu et réalisé par Pierre de Tartas. Préfacées par le professeur de Vernejoul & Jean Rostand de l'Académie Française. 3 vols. Vol. 1 illustré par Hans Erni, Vol. 2 illustré par Pierre-Yves Tremois, Vol. 3 illustré par Michel Ciry.

Facsimile of the 1585 fourth and best edition of Paré's Oeuvres, published in 3 vols., each volume additionally illustrated by a distinguished French 20th century artist. 5000 numbered sets were issued in vario…