Entry Nos. 2300–2399

1950 CE

#2352

A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.

1952 CE

#2353

Chemotherapy of human tuberculosis with hydrazine derivatives of isonicotinic acid. (Preliminary report of representative cases.)

Introduction of isoniazid. With I. J. Selikoff and G. G. Omstein. See also Amer. Rev. Tuberc., 1952, 65, 257-442.

1925 CE

#2354

Development of our knowledge of tuberculosis.

1931 CE

#2355

Historie de la tuberculose.

1936 CE

#2356

A short history of tuberculosis.

1936 CE

#2357

Tuberculosis.

Clio Medica series.

1937 CE

#2358

The control of tuberculosis in England, past and present.

1946 CE

#2359

Chemotherapy of tuberculosis. Researches during the past 100 years.

1955 CE

#2360

Historical chronology of tuberculosis. 2nd ed.

1496 CE–1497 CE

#2362

Tractatus de pestilentiali scorra sive mala de Franzos: originem remediaqu[ue] eiusdem continens.

Grünpeck was first to record mixed primary lesions, multiple primary lesions, and to note the second incubation period of syphilis. A translation of the above is in Arch. Derm. Syph. (Chicago), 1930, 22, 430. Dig…

1497 CE

#2363

Libellus de Epidemia, quam uulgo morbum Gallicum uocant,

One of the earliest treatises on syphilis, and one of the few medical books printed by Aldus Manutius in the 15th century. Leoniceno included a good description of syphilitic hemiplegia. He believed that syphilis was …

1530 CE

#2364

Syphilis sive morbus gallicus.

The most famous of all medical poems. It epitomized contemporary knowledge of syphilis, gave to it its present name, and recognized a venereal cause. Fracastorius refers to mercury as a remedy. First complete English …

1527 CE

#2365

Liber de morbo gallico.

Includes a description of the neurological manifestations of syphilis. Though this work bears the date 1507, Peter Krivatsy, provided evidence that this edition was printed in 1527. See Krivatsy, "Nicola Massa's Liber…

1533 CE

#2366

Morbi gallici novum ac utilissimum opusculum quo vera et omnimoda ejus cura percipi potest.

Mattioli considered mercury a specific in the treatment of syphilis. He was probably the first to work extensively on syphilis of the newborn. He is better known for his commentary on Dioscorides.

1539 CE

#2367

Tractado cótra el mal serpentino.

Diaz de Isla, a Barcelonese surgeon, wrote of a disease “previously unknown, unseen and undescribed”, which appeared in Barcelona in 1493 and which was obviously syphilis. This is probably the earliest ref…

1552 CE

#2368

La méthode curatoire de la maladie venerienne.

De Héry made a fortune from treating syphilitic patients. He recommended mercurial inunctions and guaiac internally.

1553 CE

#2369

Von der frantzösischen kranckheit drey Bücher.

Paracelsus suggested the hereditary transmission of syphilis and advocated mercury internally, as an antisyphilitic. He called the disease “French gonorrhoea” and thus started the confusion which lasted un…

1563 CE

#2370

De morbo gallico.

Falloppius was one of the first prominent opponents of the use of mercury in syphilis. He distinguished syphilitic and non-syphilitic condylomata.

1563 CE

#2371

Certaine works of chirurgerie.

Includes the first mention of syphilis in the English literature. Facsimile reprint, New York, Da Capo Press, 1971.

1566 CE–1567 CE

#2372

De morbo gallico omnia quae extant. 3 vols.

A collection of important writings on syphilis to 1500. Boerhaave published a revision of this work in 1728, covering the period 1495-1566.

1579 CE

#2373

A short and profitable treatise touching the cure of the morbus gallicus by unctions.

William Clowes, the greatest of the Elizabethan surgeons, published the first original English treatise on syphilis. It was his first work; it demonstrates the prevalence of the disease at that time (Clowes says that …

1579 CE

#2374

Deluis venereae curatione perfectissima liber.

French translation, Paris, 1879.

1684 CE

#2375

Tuta, ac efficax luis venereae, saepe absque mercurio, ac semper absque salivatione mercuriali curando methodus.

Abercromby advanced the idea that syphilis was caused by a parasite, and promoted mercury as a treatment. Digital facsimile from Google Books at this link.

1774 CE

#2376

Morborum antiquitates.

Pp. 85-100: “Lists 191 semeiological varieties of syphilis described in the period” (Garrison).

1786 CE

#2377

A treatise on the venereal disease.

In Hunter's day venereal diseases were thought to be due to a single poison. To test this theory Hunter experimented with matter taken from a gonorrhoeal patient who, unknown to Hunter, also had syphilis. Hunter maint…

1793 CE

#2378

A treatise on gonorrhoea virulenta, and lues venerea. 2 vols.

Bell was the first to differentiate between gonorrhoea and syphilis.

1835 CE–1836 CE

#2379

Treatment of the venereal disease by the hydriodate of potash, or iodide of potassium.

Wallace introduced potassium iodide in the treatment of syphilis, reporting good results in 139 patients.

1837 CE

#2380

Practical observations on the venereal disease, and on the use of mercury.

“Colles’s law” is stated on. p. 304. Colles introduced small doses of mercury in the treatment of syphilis. He was Professor of Surgery at Dublin.

1838 CE

#2381

Traité pratique des maladies vénériennes.

Includes the description of “Ricord’s chancre”, the initial lesion in syphilis. Ricord re-demonstrated the specific character of syphilis and divided it into the three stages, primary, secondary, and…

1854 CE

#2383

Traité de la syphilis des nouveau-nés et des enfants à la mamelle.

An important work on congenital syphilis. English translation, 1859.

1856 CE

#2384

First demonstration of the experimental inoculability of syphilis. The information is given in a discussion on the subject by the Society of Physicians of the Palatinate; it appeared anonymously, without title, and id…

1858 CE

#2385

Ueber die Natur der constitutionell-syphilitischen Affectionen.

Virchow’s great work on the pathology of syphilis confirmed the fact that it was a disease which involved all organs and tissues of the body and showed that the causal organism was transferred through the blood …

1858 CE

#2386

Report on the effects of infantile syphilis in marring the development of the teeth.

Hutchinson of St. Bartholomew’s Hospital, is memorable for his original description of the notched incisors (“Hutchinson’s teeth”) in congenital syphilis. His name is also associated with &ldqu…

1861 CE

#2387

Untersuchungen über den constitutionellen Mercurialismus und sein Verhältniss zur constitutionellen Syphilis.

1862 CE

#2388

Della trasmissione delle sifilide mediante la inoculazione del sangue.

Proof of the possibility of transmission of syphilis by blood transfusion.

1863 CE

#2389

On the syphilitic affections of internal organs.

Wilks’s outstanding work was on visceral syphilis, a subject which he was one of the first to study.

1865 CE

#2390

Sulla sifilide per allattamento.

Profeta’s law – a non-syphilitic child born of syphilitic parents is immune.

1876 CE–1877 CE

#2391

On irregular and defective tooth development.

“Moon’s molars”, the first molars in congenital syphilitics.

1878 CE–1879 CE

#2392

Das Contagium der Syphilis. Eine experimentelle Studie.

Klebs inoculated syphilis into apes and probably saw the spirochete before Schaudinn and Hoffmann.

1886 CE

#2393

La syphilis héréditaire tardive.

Fournier, one of the greatest syphilologists, did more than any other person to develop the knowledge regarding congenital syphilis. Through his writings, the importance of syphilis as a cause of degenerative diseases…

1889 CE

#2394

Expériences sur la toxicité du bismuth.

Balzer was the first to suggest bismuth in the treatment of syphilis.

1897 CE

#2395

Les chancres extra-génitaux.

1895 CE

#2396

Therapeutische Versuche bei Syphilis.

Jarisch-Herxheimer reaction; see also No. 2397.

1902 CE

#2397

Ueber eine bei Syphilitischen vorkommende Quecksilberreaktion.

See No. 2396.

1903 CE–1904 CE

#2398

Études expérimentales sur la syphilis.

Metchnikoff and Roux successfully transmitted syphilis from man to the higher apes. Although not the first to do this, they recorded much new information concerning the disease.

1905 CE

#2399

Vorläufiger Bericht über das Vorkommen von Spirochaeten in syphilitischen Krankheitsprodukten und bei Papillomen.

On March 3, 1905, Schaudinn discovered the causal organism of syphilis Spirochaeta pallida, in serum obtained from a genital lesion by Hoffmann. Schaudinn later renamed the spirochete Treponema pallidum.